MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1901 to 1950 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
diaphanous protein homolog 1 (diaphanous-related formin 1) (drf1). [swissprot;acc:o60610]	1158	DIAPH1	Low confidence	200.185	195.622	1.02333
diaphanous protein homolog 3 (diaphanous-related formin 3) (drf3) (fragment). [swissprot;acc:q9nsv4]	1174	DIAPH3		200.258	195.713	1.02322
dihydrofolate reductase (ec 1.5.1.3). [swissprot;acc:p00374]	1591	no value	High confidence	225.119	228.769	1.01621
	1995		Low confidence	201.656	197.802	1.01948
dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (ec 2.3.1.12) (e2) (pdc-e2) (70 kda mitochondrial autoantigen of primary biliary cirrhosis) (pbc) (m2 antigen complex 70 kda subunit). [swissprot;acc:p10515]	1298	DLAT	High confidence	206.482	211.404	1.02384
	1338		Low confidence	204.159	199.739	1.02213
dihydrolipoamide dehydrogenase, mitochondrial precursor (ec 1.8.1.4) (glycine cleavage system l protein). [swissprot;acc:p09622]	1039	DLD	High confidence	207.719	214.236	1.03137
	2162		Low confidence	200.565	196.809	1.01908
dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor (ec 2.3.1.61) (e2) (e2k). [swissprot;acc:p36957]	1462	DLSTP	High confidence	205.817	209.851	1.0196
	1959		Low confidence	200.486	196.63	1.01961
dihydroorotate dehydrogenase, mitochondrial precursor (ec 1.3.3.1) (dihydroorotate oxidase) (dhodehase) (fragment). [swissprot;acc:q02127]	653	DHODH		203.975	198.304	1.0286
	2392		High confidence	214.966	215.799	1.00388
dihydropteridine reductase (ec 1.6.99.7) (hdhpr) (quinoid dihydropteridine reductase). [swissprot;acc:p09417]	3060	QDPR	Low confidence	199.619	196.366	1.01657
dihydropyrimidine dehydrogenase [nadp+] precursor (ec 1.3.1.2) (dpd) (dhpdhase) (dihydrouracil dehydrogenase) (dihydrothymine dehydrogenase). [swissprot;acc:q12882]	1009	no value	High confidence	229.116	221.823	1.03288
	3692		Low confidence	203.643	200.868	1.01382
dimeric dihydrodiol dehydrogenase; 3-deoxyglucosone reductase. [refseq;acc:nm_014475]	2001	DHDH		201.524	197.677	1.01946
	2213		High confidence	210.127	211.475	1.00642
dimethylaniline monooxygenase [n-oxide forming] 1 (ec 1.14.13.8) (fetal hepatic flavin-containing monooxygenase 1) (fmo 1) (dimethylaniline oxidase 1). [swissprot;acc:q01740]	211	FMO1	Low confidence	209.768	199.756	1.05012
	2288		High confidence	216.607	215.458	1.00533
dimethylaniline monooxygenase [n-oxide forming] 2 (ec 1.14.13.8) (pulmonary flavin-containing monooxygenase 2) (fmo 2) (dimethylaniline oxidase 2) (fmo 1b1). [swissprot;acc:q99518]	210	FMO2	Low confidence	209.782	199.761	1.05016
	2286		High confidence	216.608	215.456	1.00535
dimethylaniline monooxygenase [n-oxide forming] 3 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 3) (fmo 3) (dimethylaniline oxidase 3) (fmo form 2) (fmo ii). [swissprot;acc:p31513]	209	FMO3	Low confidence	209.778	199.757	1.05017
	2276		High confidence	216.613	215.448	1.00541
dimethylaniline monooxygenase [n-oxide forming] 4 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 4) (fmo 4) (dimethylaniline oxidase 4). [swissprot;acc:p31512]	213	FMO4	Low confidence	209.765	199.755	1.05011
	2289		High confidence	216.605	215.46	1.00531
dimethylaniline monooxygenase [n-oxide forming] 5 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 5) (fmo 5) (dimethylaniline oxidase 5). [swissprot;acc:p49326]	190	FMO5	Low confidence	210.557	200.074	1.0524
	2271		High confidence	216.622	215.436	1.00551
dipeptidyl aminopeptidase-like protein 6 (dipeptidylpeptidase vi) (dipeptidylpeptidase 6) (dipeptidyl peptidase iv like protein) (dipeptidyl aminopeptidase-related protein) (dppx). [swissprot;acc:p42658]	429	DPP6	Low confidence	202.75	195.879	1.03508
	1516		High confidence	213.267	209.511	1.01793
dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]	395	DPP8		218.827	238.407	1.08948
	4742		Low confidence	196.768	197.824	1.00537
dipeptidylpeptidase 10; dipeptidyl peptidase iv-related protein 3. [refseq;acc:nm_020868]	430	DPP10		202.75	195.88	1.03507
	1515		High confidence	213.267	209.511	1.01793
dipeptidylpeptidase 9; dipeptidyl peptidase 9; dipeptidyl peptidase iv-related protein-2. [refseq;acc:nm_139159]	394	DPP9		218.827	238.407	1.08948
	4743		Low confidence	196.767	197.822	1.00536
diphosphomevalonate decarboxylase (ec 4.1.1.33) (mevalonate pyrophosphate decarboxylase) (mevalonate (diphospho)decarboxylase). [swissprot;acc:p53602]	868	MVD	High confidence	233.298	242.571	1.03975
	3163		Low confidence	202.715	199.486	1.01619
diphthamide biosynthesis-like protein 2. [refseq;acc:nm_001384]	1202	DPH2	High confidence	227.274	233.041	1.02537
	3723		Low confidence	201.544	198.846	1.01357
discoidin domain receptor 2 precursor (ec 2.7.1.112) (receptor protein-tyrosine kinase tkt) (tyrosine-protein kinase tyro 10) (neurotrophic tyrosine kinase, receptor-related 3). [swissprot;acc:q16832]	2724	DDR2		200.78	197.329	1.01749
discs, large homolog 5 (placenta and prostate dlg) (discs large protein p-dlg). [swissprot;acc:q8tdm6]	3911	DLG5		207.449	204.872	1.01258
dishevelled-associated activator of morphogenesis 1. [refseq;acc:nm_014992]	3531	DAAM1		202.898	199.949	1.01475
disks large-associated protein 1 (dap-1) (guanylate kinase-associated protein) (hgkap) (sap90/psd-95-associated protein 1) (sapap1) (psd- 95/sap90 binding protein 1). [swissprot;acc:o14490]	114	DLGAP1		197.779	211.983	1.07182
	701		High confidence	220.438	209.118	1.05413
disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	110	no value	Low confidence	197.752	212.031	1.07221
	708		High confidence	220.438	209.118	1.05413
disks large-associated protein 3 (dap-3) (sap90/psd-95-associated protein 3) (sapap3) (psd-95/sap90 binding protein 3) (fragment). [swissprot;acc:o95886]	108	DLGAP3	Low confidence	197.731	212.069	1.07251
	706		High confidence	220.438	209.118	1.05413
disks large-associated protein 4 (dap-4) (sap90/psd-95-associated protein 4) (sapap4) (psd-95/sap90 binding protein 4). [swissprot;acc:q9y2h0]	115	DLGAP4	Low confidence	197.779	211.983	1.07182
	710		High confidence	220.438	209.118	1.05413

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.