MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1801 to 1850 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
adp-ribosylation factor 1. [swissprot;acc:p32889]	1557	ARF1	Squared	Subtracted	25629.5	28203.8	2574.3
	1755			Divided			1.10044
	1824		Measured		5633.44	5997	1.06454
	1892			Subtracted			363.56
	2110		Ranked		221.248	222.788	1.54
	2128			Divided			1.00696
	2175		Rooted		60.8609	62.2517	1.02285
	2222			Subtracted			1.3908
adp-ribosylation factor 3. [swissprot;acc:p16587]	1559	ARF3	Squared		25629.5	28203.8	2574.3
	1757			Divided			1.10044
	1826		Measured		5633.44	5997	1.06454
	1894			Subtracted			363.56
	2112		Ranked		221.248	222.788	1.54
	2130			Divided			1.00696
	2177		Rooted		60.8609	62.2517	1.02285
	2224			Subtracted			1.3908
adp-ribosylation factor 4. [swissprot;acc:p18085]	1552	ARF4	Squared		25629.5	28203.8	2574.3
	1750			Divided			1.10044
	1819		Measured		5633.44	5997	1.06454
	1887			Subtracted			363.56
	2105		Ranked		221.248	222.788	1.54
	2123			Divided			1.00696
	2170		Rooted		60.8609	62.2517	1.02285
	2217			Subtracted			1.3908
adp-ribosylation factor gtpase activating protein 1 (adp-ribosylation factor 1 gtpase activating protein) (arf1 gap) (arf1-directed gtpase- activating protein) (gap protein). [swissprot;acc:q8n6t3]	492	ARFGAP1	Squared		27516.2	32720	5203.8
	552			Divided			1.18912
	768		Measured	Subtracted	6654.42	7296.51	642.09
	982			Divided			1.09649
	1314		Rooted	Subtracted	68.657	71.3161	2.6591
	1459			Divided			1.03873
	2156		Ranked		200.063	198.71	1.00681
	2219			Subtracted			1.353
adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	1563	ARFGAP3	Squared		25629.5	28203.8	2574.3
	1761			Divided			1.10044
	1830		Measured		5633.44	5997	1.06454
	1898			Subtracted			363.56
	2116		Ranked		221.248	222.788	1.54
	2137			Divided			1.00696
	2181		Rooted		60.8609	62.2517	1.02285
	2228			Subtracted			1.3908
adp-ribosylation factor-like protein 1. [swissprot;acc:p40616]	1383	ARL1	Squared		28122.9	30941.9	2819
	1573		Measured		6035.6	6464.5	428.9
	1619			Divided			1.07106
	1773		Squared		28122.9	30941.9	1.10024
	1868		Rooted		63.2302	65.1018	1.0296
	1873			Subtracted			1.8716
	2613		Ranked	Divided	215.497	215.799	1.0014
	2623			Subtracted			0.302
adp-ribosylation factor-like protein 3. [swissprot;acc:p36405]	1342	ARL3	Squared		27060.6	29916.8	2856.2
	1530		Measured		5916.05	6350.53	434.48

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.