MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1601 to 1650 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

Rank	Hugo	description	Interaction Map	red	green	network_comparison
801	CTNNB1	beta-catenin (pro2286). [swissprot;acc:p35222]	High confidence	224.445	214.894	1.04445
	PDCD6	programmed cell death protein 6 (probable calcium-binding protein alg- 2). [swissprot;acc:o75340]	Low confidence	202.522	197.311	1.02641
802	C3orf37	dc12 protein. [refseq;acc:nm_020187]		203.345	198.117	1.02639
	TEX28P2	testis-specific protein tex28. [swissprot;acc:o15482]	High confidence	212.386	221.785	1.04425
803	C3orf60	similar to nuclear protein e3-3 orf1. [sptrembl;acc:q9bu61]
	RPN1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kda subunit precursor (ec 2.4.1.119) (ribophorin i) (rpn-i). [swissprot;acc:p04843]	Low confidence	199.573	194.441	1.02639
804	NEGR1	a kindred of iglon. [refseq;acc:nm_173808]	High confidence	212.386	221.785	1.04425
	TSFM	elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	Low confidence	204.519	199.267	1.02636
805	ANKRA2	ankyrin-repeat family a protein 2 (rfxank-like 2). [swissprot;acc:q9h9e1]	High confidence	212.386	221.785	1.04425
	SYNJ1	synaptojanin 1 (ec 3.1.3.36) (synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1). [swissprot;acc:o43426]	Low confidence	198.496	193.399	1.02635
806	ATP6V1C1	vacuolar atp synthase subunit c (ec 3.6.3.14) (v-atpase c subunit) (vacuolar proton pump c subunit). [swissprot;acc:p21283]		202.369	197.173
	GPR84	inflammation-related g protein-coupled receptor ex33. [refseq;acc:nm_020370]	High confidence	212.386	221.785	1.04425
807	PNKD	myofibrillogenesis regulator 1; trans-activated by hepatitis c virus core protein 2; likely ortholog of mouse brain protein 17. [refseq;acc:nm_022572]	Low confidence	200.782	195.631	1.02633
	PPT1	palmitoyl-protein thioesterase 1 precursor (ec 3.1.2.22) (palmitoyl- protein hydrolase 1). [swissprot;acc:p50897]	High confidence	212.386	221.785	1.04425
808	HDLBP	vigilin (high density lipoprotein-binding protein) (hdl-binding protein). [swissprot;acc:q00341]	Low confidence	201.169	196.014	1.0263
	NAPB	beta-soluble nsf attachment protein (snap-beta) (n-ethylmaleimide- sensitive factor attachment protein, beta). [swissprot;acc:q9h115]	High confidence	212.386	221.785	1.04425
809	PAK1	serine/threonine-protein kinase pak 1 (ec 2.7.1.-) (p21-activated kinase 1) (pak-1) (p65-pak) (alpha-pak). [swissprot;acc:q13153]	Low confidence	202.744	197.552	1.02628
	STX16	syntaxin 16 (syn16). [swissprot;acc:o14662]	High confidence	212.386	221.785	1.04425
810	APPBP1	amyloid beta precursor protein-binding protein 1; amyloid protein-binding protein 1. [refseq;acc:nm_003905]	Low confidence	196.326	191.3	1.02627
	GOSR2	27 kda golgi snare protein (golgi snap receptor complex member 2) (membrin). [swissprot;acc:o14653]	High confidence	212.386	221.785	1.04425
811	STX1A	syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623]
	STX1B	syntaxin 1b. [swissprot;acc:q15531]	Low confidence	211.432	206.021	1.02626
812	NAPA	alpha-soluble nsf attachment protein (snap-alpha) (n-ethylmaleimide- sensitive factor attachment protein, alpha). [swissprot;acc:p54920]	High confidence	212.386	221.785	1.04425
	SLC30A1	zinc transporter 1 (znt-1). [swissprot;acc:q9y6m5]	Low confidence	206.173	200.909	1.0262
813	C20orf3	adipocyte plasma membrane-associated protein (bscv protein). [swissprot;acc:q9hdc9]	High confidence	212.386	221.785	1.04425
	SYNJ2	synaptojanin 2 (ec 3.1.3.36) (synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2) (fragment). [swissprot;acc:o15056]	Low confidence	198.561	193.492	1.0262
814	SNAP29	synaptosomal-associated protein 29 (snap-29) (vesicle-membrane fusion protein snap-29) (soluble 29 kda nsf attachment protein). [swissprot;acc:o95721]	High confidence	212.386	221.785	1.04425
	UPF1	regulator of nonsense transcripts 1 (nonsense mrna reducing factor 1) (norf1) (up-frameshift suppressor 1 homolog). [swissprot;acc:q92900]	Low confidence	202.069	196.914	1.02618
815	NFYB	nuclear transcription factor y subunit beta (nf-y protein chain b) (nf-yb) (ccaat-binding transcription factor subunit a) (cbf-a) (caat- box dna binding protein subunit b). [swissprot;acc:p25208]		203.907	198.706	1.02617
	STX1B	syntaxin 1b. [swissprot;acc:q15531]	High confidence	212.386	221.785	1.04425
816	CDC25A	m-phase inducer phosphatase 1 (ec 3.1.3.48) (dual specificity phosphatase cdc25a). [swissprot;acc:p30304]	Low confidence	207.541	202.25	1.02616
	MRPL28	melanoma antigen p15 (melanoma-associated antigen recognized by t lymphocytes). [swissprot;acc:q13084]	High confidence	212.386	221.785	1.04425
817	LSM6	u6 snrna-associated sm-like protein lsm6 (sm protein f). [swissprot;acc:q9y4y8]	Low confidence	202.15	197.002	1.02613
	RFXANK	dna-binding protein rfxank (regulatory factor x subunit b) (rfx-b) (ankyrin repeat family a protein 1). [swissprot;acc:o14593]	High confidence	212.386	221.785	1.04425
818	RGL1	ral guanine nucleotide dissociation stimulator-like 1 (ralgds-like 1). [swissprot;acc:q9nzl6]		168.592	161.452	1.04422
	SERHL2	serine hydrolase-like protein (ec 3.1.-.-). [swissprot;acc:q9h4i8]	Low confidence	208.488	203.181	1.02612
819	no value	aspartate beta-hydroxylase isoform b; junctin isoform 1; junctate; aspartyl/asparaginyl-beta-hydroxylase; peptide-aspartate beta-dioxygenase; humbug. [refseq;acc:nm_032468]
	POLR2I	dna-directed rna polymerase ii 14.5 kda polypeptide (ec 2.7.7.6) (rpb9) (rpb14.5). [swissprot;acc:p36954]	High confidence	228.563	238.668	1.04421
820	ABLIM2	actin binding lim protein 2. [refseq;acc:nm_032432]	Low confidence	208.488	203.181	1.02612
	MRPS2	mitochondrial 28s ribosomal protein s2 (mrp-s2) (cgi-91). [swissprot;acc:q9y399]	High confidence	221.716	231.501	1.04413
821	IMP4	u3 snornp protein 4 homolog. [refseq;acc:nm_033416]		221.676	231.453	1.0441
	PEX5	peroxisomal targeting signal 1 receptor (peroxismore receptor 1) (peroxisomal c-terminal targeting signal import receptor) (pts1-bp) (peroxin-5) (pts1 receptor). [swissprot;acc:p50542]	Low confidence	208.488	203.181	1.02612
822	ABLIM1	actin-binding lim protein 1 isoform a; lim actin-binding protein 1; limatin; actin-binding lim protein. [refseq;acc:nm_002313]
	EIF3B	eukaryotic translation initiation factor 3 subunit 9 (eif-3 eta) (eif3 p116) (eif3 p110) (eif3b). [swissprot;acc:p55884]	High confidence	243.067	232.805	1.04408
823	C16orf80	transcription factor iib. [refseq;acc:nm_013242]		206.068	197.471	1.04354
	RRAGC	ras-related gtp binding c; rag c protein. [refseq;acc:nm_022157]	Low confidence	186.275	181.537	1.0261
824	SFRS8	splicing factor, arginine/serine-rich 8 (suppressor of white apricot protein homolog). [swissprot;acc:q12872]	High confidence	206.068	197.471	1.04354
	ZNF423	olf-1/ebf associated zinc finger protein; smad- and olf-interacting zinc finger protein. [refseq;acc:nm_015069]	Low confidence	204.922	199.711	1.02609
825	no value	early hematopoietic zinc finger. [refseq;acc:nm_015461]		204.914	199.706	1.02608
	WIPF1	wiskott-aldrich syndrome protein interacting protein (wasp interacting protein) (prpl-2 protein). [swissprot;acc:o43516]	High confidence	206.214	197.614	1.04352

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.