MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

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Showing element 1558 to 1607 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
skeletal muscle and kidney enriched inositol phosphatase isoform 1; 43-kda form skeletal muscle and kidney enriched inositol phosphatase. [refseq;acc:nm_016532]	2994	no value	Ranked	High confidence
			Squared
			Rooted
small edrk-rich factor 2. [refseq;acc:nm_005770]	2947	SERF2	Measured
			Ranked
			Squared
			Rooted
small nuclear ribonucleoprotein associated protein n (snrnp-n) (sm protein n) (sm-n) (smn) (sm-d) (tissue-specific splicing protein). [swissprot;acc:p14648]	3004	SNRPN	Measured
			Ranked
			Squared
			Rooted
small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678]	3012	SNRPB	Measured
			Ranked
			Squared
			Rooted
snrna activating protein complex 50 kda subunit (snapc 50 kda subunit) (proximal sequence element-binding transcription factor beta subunit) (pse-binding factor beta subunit) (ptf beta subunit). [swissprot;acc:q92966]	2849	SNAPC3	Measured
			Ranked
			Squared
			Rooted
solute carrier family 21 member 15 (organic anion transporter polypeptide-related protein 4) (oatp-rp4) (oatprp4). [swissprot;acc:q9h2y9]	2965	SLCO5A1	Measured
			Ranked
			Squared
			Rooted
	5034		Ranked	Low confidence
	5035		Measured
			Squared
			Rooted
solute carrier family 36 member 1; proton / amino acid symporter; lysosomal amino acid transporter 1. [refseq;acc:nm_078483]	3026	SLC36A1	Measured	High confidence
			Ranked
			Squared
			Rooted
sorting nexin 16. [swissprot;acc:p57768]	3108	SNX16	Measured
			Ranked
			Squared
			Rooted
sparc precursor (secreted protein acidic and rich in cysteine) (osteonectin) (on) (basement membrane protein bm-40). [swissprot;acc:p09486]	3062	SPARC	Measured
			Ranked
			Squared
			Rooted
sparc-like protein 1 precursor (high endothelial venule protein) (hevin) (mast 9). [swissprot;acc:q14515]	2899	SPARCL1	Measured
			Ranked
			Squared
			Rooted
spartin; trans-activated by hepatitis c virus core protein 1. [refseq;acc:nm_015087]	2987	SPG20	Measured
			Ranked
			Squared
			Rooted
speckle-type poz protein. [swissprot;acc:o43791]	3031	SPOP	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.