MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1558 to 1607 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	network_comparison	green
dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]	395	DPP8	Divided	218.827	1.08948	238.407
dipeptidylpeptidase 10; dipeptidyl peptidase iv-related protein 3. [refseq;acc:nm_020868]	1515	DPP10		213.267	1.01793	209.511
	1525		Subtracted		3.756
dipeptidylpeptidase 9; dipeptidyl peptidase 9; dipeptidyl peptidase iv-related protein-2. [refseq;acc:nm_139159]	367	DPP9		218.827	19.58	238.407
	394		Divided		1.08948
diphosphomevalonate decarboxylase (ec 4.1.1.33) (mevalonate pyrophosphate decarboxylase) (mevalonate (diphospho)decarboxylase). [swissprot;acc:p53602]	809	MVD	Subtracted	233.298	9.273	242.571
	868		Divided		1.03975
diphthamide biosynthesis-like protein 2. [refseq;acc:nm_001384]	1114	DPH2	Subtracted	227.274	5.767	233.041
	1202		Divided		1.02537
disks large-associated protein 1 (dap-1) (guanylate kinase-associated protein) (hgkap) (sap90/psd-95-associated protein 1) (sapap1) (psd- 95/sap90 binding protein 1). [swissprot;acc:o14490]	700	DLGAP1	Subtracted	220.438	11.32	209.118
	701		Divided		1.05413
disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	707	no value	Subtracted		11.32
	708		Divided		1.05413
disks large-associated protein 3 (dap-3) (sap90/psd-95-associated protein 3) (sapap3) (psd-95/sap90 binding protein 3) (fragment). [swissprot;acc:o95886]	705	DLGAP3	Subtracted		11.32
	706		Divided		1.05413
disks large-associated protein 4 (dap-4) (sap90/psd-95-associated protein 4) (sapap4) (psd-95/sap90 binding protein 4). [swissprot;acc:q9y2h0]	709	DLGAP4	Subtracted		11.32
	710		Divided		1.05413
disrupter of silencing 10. [refseq;acc:nm_020368]	1905	UTP3		191.411	1.01034	193.39
	1981		Subtracted		1.979
dj1099d15.1 (putative dnaj protein). [sptrembl;acc:q9h4j9]	641	no value		244.842	12.265	232.577
	724		Divided		1.05274
dj132f21.2 (contains a novel protein similar to the l82e from drosophila) (fragment). [sptrembl;acc:q9h125]	2039	C20orf118	Subtracted	218.79	1.809	216.981
	2060		Divided		1.00834
dj153g14.2 (possible ca binding protein similar to nefa) (fragment). [sptrembl;acc:q9ujn8]	744	no value	Subtracted	225.996	10.461	215.535
	776		Divided		1.04854
dj18d14.4 (cytochrome p450, subfamily iva, polypeptide 11). [sptrembl;acc:q9ntl5]	1255	CYP4A22	Subtracted	218.368	5.148	213.22
	1287		Divided		1.02414
dj408b20.3 (novel protein similar to 60s acidic ribosomal protein p2 (rplp2)). [sptrembl;acc:q9h5a9]	496	no value	Subtracted	235.18	15.239	250.419
	576		Divided		1.0648
dj470l14.3 (novel protein similar to the arp2/3 protein complex subunit p21-arc (arc21)). [sptrembl;acc:q9h5b6]	2599		Subtracted	224.891	0.304	225.195
	2621		Divided		1.00135
dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]	2408			194.407	1.00362	193.706
	2439		Subtracted		0.701
dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4]	3025	HMG1L1	Divided	0.00001	1	0.00001
			Subtracted	0	0	0
dj681n20.2 (novel protein similar to ferritin, light polypeptide (ftl)). [sptrembl;acc:q9byw6]	699	no value		220.438	11.32	209.118
	700		Divided		1.05413
dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	1125			204.404	1.02748	210.022
	1133		Subtracted		5.618
dj756n5.1.1 (continues in em:al133324 as dj1161h23.3) (fragment). [sptrembl;acc:q9h430]	222	MYH7B	Divided	112	1.125	126
	544		Subtracted		14
dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]	132	NCBP2L		229.406	32.711	196.695
	177		Divided		1.1663
dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03]	1879	no value	Subtracted	210.592	2.237	208.355
	1881		Divided		1.01074
dj947l8.1.1 (novel cub and sushi (scr repeat) domain protein) (fragment). [sptrembl;acc:q9h4v7]	1304		Subtracted	218.509	4.861	213.648
	1329		Divided		1.02275
dj947l8.1.6 (novel cub and sushi (scr repeat) domain protein) (fragment). [sptrembl;acc:q9h4w2]	1302	CSMD1	Subtracted		4.861
	1326		Divided		1.02275
dj999l4.1 (novel protein similar to ribosomal protein l12 (rpl12)). [sptrembl;acc:q9nq02]	248	no value	Subtracted	243.583	23.944	267.527

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.