MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1308 to 1357 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
putative tumor suppressor 101f6. [refseq;acc:nm_007022]	3051	CYB561D2	Rooted	High confidence
	5045		Ranked	Low confidence
	5046		Measured
			Squared
			Rooted
r3h domain (binds single-stranded nucleic acids) containing-like. [refseq;acc:nm_178491]	3132	R3HDML	Measured	High confidence
			Ranked
			Squared
			Rooted
rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150]	3119	no value	Measured
			Ranked
			Squared
			Rooted
rab gdp dissociation inhibitor beta (rab gdi beta) (gdi-2). [swissprot;acc:p50395]	3193	GDI2	Measured
			Ranked
			Squared
			Rooted
rab geranylgeranyltransferase alpha subunit (ec 2.5.1.-) (rab geranyl- geranyltransferase alpha subunit) (rab gg transferase alpha) (rab ggtase alpha). [swissprot;acc:q92696]	3134	RABGGTA	Measured
			Ranked
			Squared
			Rooted
rala binding protein 1; rala-binding protein. [refseq;acc:nm_006788]	3212	RALBP1	Measured
			Ranked
			Squared
			Rooted
ran binding protein 3 isoform ranbp3-d; ran-binding protein-3. [refseq;acc:nm_007322]	3202	RANBP3	Measured
			Ranked
			Squared
			Rooted
rap1 gtpase-gdp dissociation stimulator 1 (smg p21 stimulatory gdp/gtp exchange protein) (smg gds protein) (exchange factor smggds). [swissprot;acc:p52306]	5033	RAP1GDS1	Ranked	Low confidence
	5034		Measured
			Squared
			Rooted
ras-related protein rab-11a (rab-11) (24kg) (yl8). [swissprot;acc:p24410]	3112	RAB11A	Measured	High confidence
			Ranked
			Squared
			Rooted
ras-related protein rab-11b (gtp-binding protein ypt3). [swissprot;acc:q15907]	2764	RAB11B	Measured
			Ranked
			Squared
			Rooted
ras-related protein rab-1a (ypt1-related protein). [swissprot;acc:p11476]	2961	RAB1A	Measured
			Ranked
			Squared
			Rooted
ras-related protein rab-1b. [swissprot;acc:q9h0u4]	2807	RAB1C	Measured
			Ranked
			Squared
			Rooted
ras-related protein rab-2a. [swissprot;acc:p08886]	3110	RAB2A	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.