MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 130 to 179 of 321 in total

Hugo  : no value
Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	red	green	network_comparison
1087	zinc finger protein 277. [swissprot;acc:q9nrm2]	236.679	243.679	1.02958
1090	similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9]	226.218	232.88	1.02945
1091	block 23. [sptrembl;acc:q8nhw5]	226.205	232.858	1.02941
1102	40s ribosomal protein s27 (metallopan-stimulin 1) (mps-1). [swissprot;acc:p42677]	229.442	235.974	1.02847
1111	apoptosis inhibitor fksg2. [swissprot;acc:q9hau6]	217.99	212.123	1.02766
1125	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	204.404	210.022	1.02748
1127	nucleolar protein nop5 (nucleolar protein 5) (nop58) (hspc120). [swissprot;acc:q9y2x3]	239.219	232.837	1.02741
1131	vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670]	218.484	212.675	1.02731
1148	ubiquitin. [swissprot;acc:p02248]	209.061	203.518	1.02724
1161	kappa b-ras 1. [refseq;acc:nm_020345]	220.758	215.097	1.02632
1170	cytokine-like nuclear factor n-pac. [refseq;acc:nm_032569]	219.399	213.784	1.02626
1172	transducin-like enhancer protein 1 (esg1). [swissprot;acc:q04724]	219.375	213.767	1.02623
1186	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]	218.402	212.904	1.02582
1189	alpha-1-acid glycoprotein 2 precursor (agp 2) (orosomucoid 2) (omd 2). [swissprot;acc:p19652]	209.649	204.406	1.02565
1206	integral membrane protein cii-3b. [sptrembl;acc:o75609]	207.646	212.891	1.02526
1208	signal recognition particle receptor alpha subunit (sr-alpha) (docking protein alpha) (dp-alpha). [swissprot;acc:p08240]	224.878	219.342	1.02524
1214	kinesin-like protein kif13b (kinesin-like protein gakin). [swissprot;acc:q9nqt8]	214.364	219.759	1.02517
1233	phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]	212.724	207.637	1.0245
1235	keratin associated protein 9-4; keratin associated protein 9.4. [refseq;acc:nm_033191]	219.356	224.723	1.02447
1236	keratin associated protein 4-10; keratin associated protein 4.10. [refseq;acc:nm_033060]	219.354	224.699	1.02437
1237	keratin associated protein 4-2; keratin associated protein 4.2. [refseq;acc:nm_033062]
1238	keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4]
1239	keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]
1240	keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059]		224.7
1241	keratin associated protein 4.9 (fragment). [sptrembl;acc:q9byq8]
1242	keratin associated protein 4-12; keratin associated protein 4.12. [refseq;acc:nm_031854]
1243	keratin associated protein 1.5. [refseq;acc:nm_031957]		224.699
1246	keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]
1249	alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [swissprot;acc:q9nvd7]		224.7
1256	keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]		224.699
1322	endo-beta-n-acetylglucosaminidase. [refseq;acc:nm_022759]	159.86	156.275	1.02294
1329	dj947l8.1.1 (novel cub and sushi (scr repeat) domain protein) (fragment). [sptrembl;acc:q9h4v7]	218.509	213.648	1.02275
1337	galactose-1-phosphate uridylyltransferase (ec 2.7.7.12) (gal-1-p uridylyltransferase) (udp-glucose--hexose-1-phosphate uridylyltransferase). [swissprot;acc:p07902]	215.162	210.412	1.02257
1352	repressor of estrogen receptor activity; b-cell associated protein. [refseq;acc:nm_007273]	211.513	206.941	1.02209
1385	dead (asp-glu-ala-asp) box polypeptide 47; hqp0256 protein. [refseq;acc:nm_016355]	218.47	213.875	1.02148
1423	cysteine-rich protein 1 (cysteine-rich intestinal protein) (crip) (cysteine-rich heart protein) (hcrhp). [swissprot;acc:p50238]	221.152	216.659	1.02074
1435	myosin vi. [swissprot;acc:q9um54]	220.987	225.468	1.02028
1442	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]	225.039	229.573	1.02015
1452	cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551]	160.381	163.554	1.01978
1463	pnas-18. [sptrembl;acc:q9bzu3]	161.056	164.211	1.01959
1464	poly (adp-ribose) glycohydrolase. [refseq;acc:nm_003631]	217.351	213.18	1.01957
1477	transformer-2 protein homolog (tra-2 alpha). [swissprot;acc:q13595]	215.328	211.267	1.01922
1498	neurotrimin precursor (hnt). [swissprot;acc:q9p121]	224.022	219.924	1.01863
1502	uridine kinase-like 1. [swissprot;acc:q9nwz5]	218.084	214.149	1.01838
1523	putative ankyrin-repeat containing protein. [refseq;acc:nm_025185]	219.306	223.179	1.01766
1562	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]	167.687	170.455	1.01651
1568	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	221.128	224.767	1.01646
1569	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]
1591	dihydrofolate reductase (ec 1.5.1.3). [swissprot;acc:p00374]	225.119	228.769	1.01621
1595	adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	222.134	225.731	1.01619

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.