MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 130 to 179 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	network_comparison	green
40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	304	no value	Divided	242.339	1.1017	266.986
40s ribosomal protein s15a. [swissprot;acc:p39027]	206	RPS15A	Subtracted	241.411	25.003	266.414
	292		Divided		1.10357
40s ribosomal protein s16. [swissprot;acc:p17008]	326	RPS16	Subtracted	241.828	21.792	263.62
	391		Divided		1.09011
40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	324	no value	Subtracted	242.238	21.872	264.11
	387		Divided		1.09029
40s ribosomal protein s19. [swissprot;acc:p39019]	820	RPS19	Subtracted	234.025	9.067	224.958
	861		Divided		1.04031
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	269	no value	Subtracted	241.625	23.511	265.136
	344		Divided		1.0973
40s ribosomal protein s20. [swissprot;acc:p17075]	251	RPS20	Subtracted	243.5	23.71	267.21
	342		Divided		1.09737
40s ribosomal protein s21. [swissprot;acc:p35265]	756	RPS21	Subtracted	224.244	10.267	234.511
	790		Divided		1.04578
40s ribosomal protein s23. [swissprot;acc:p39028]	234	RPS23	Subtracted	243.944	24.251	268.195
	324		Divided		1.09941
40s ribosomal protein s24 (s19). [swissprot;acc:p16632]	1657	RPS24	Subtracted	224.091	3.093	227.184
	1690		Divided		1.0138
40s ribosomal protein s26. [swissprot;acc:p02383]	440	no value	Subtracted	210.224	16.354	226.578
	454		Divided		1.07779
40s ribosomal protein s27 (metallopan-stimulin 1) (mps-1). [swissprot;acc:p42677]	1034		Subtracted	229.442	6.532	235.974
	1102		Divided		1.02847
40s ribosomal protein s28. [swissprot;acc:p25112]	1982			200.343	1.00966	198.427
	2000		Subtracted		1.916
40s ribosomal protein s29. [swissprot;acc:p30054]	198			241.849	25.793	267.642
	277		Divided		1.10665
40s ribosomal protein s3. [swissprot;acc:p23396]	270	RPS3	Subtracted	241.612	23.507	265.119
	346		Divided		1.09729
40s ribosomal protein s30. [swissprot;acc:q05472]	1025	FAU	Subtracted	223.44	6.565	216.875
	1081		Divided		1.03027
40s ribosomal protein s3a. [swissprot;acc:p49241]	825	no value	Subtracted	225.689	8.985	234.674
	867		Divided		1.03981
40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750]	203		Subtracted	240.758	25.32	266.078
	288		Divided		1.10517
40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47]	202	RPS4Y2	Subtracted		25.321	266.079
	287		Divided		1.10517
40s ribosomal protein s5. [swissprot;acc:p46782]	275	RPS5	Subtracted	242.473	23.283	265.756
	366		Divided		1.09602
40s ribosomal protein s7 (s8). [swissprot;acc:p23821]	2126	RPS7	Subtracted	217.871	1.495	219.366
	2149		Divided		1.00686
40s ribosomal protein s8. [swissprot;acc:p09058]	1349	RPS8	Subtracted	218.64	4.591	214.049
	1397		Divided		1.02145
40s ribosomal protein s9. [swissprot;acc:p46781]	386	RPS9	Subtracted	238.986	18.798	257.784
	439		Divided		1.07866
40s ribosomal protein sa (p40) (34/67 kda laminin receptor) (colon carcinoma laminin-binding protein) (nem/1chd4) (multidrug resistance- associated protein mgr1-ag). [swissprot;acc:p08865]	755	no value	Subtracted	224.244	10.267	234.511
	789		Divided		1.04578
43 kda receptor-associated protein of the synapse (rapsyn) (acetylcholine receptor-associated 43 kda protein) (43 kda postsynaptic protein). [swissprot;acc:q13702]	2215	RAPSN	Subtracted	215.547	1.353	214.194
	2232		Divided		1.00632
44050 protein. [refseq;acc:nm_178832]	2506	C10orf83		151.386	1.0025	151.009

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.