MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	Value Type	network_comparison	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1258 to 1307 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
protein transport protein sec24a (sec24-related protein a) (fragment). [swissprot;acc:o95486]	3056	SEC24A	Ranked	High confidence
			Squared
			Rooted
protein transport protein sec24b (sec24-related protein b). [swissprot;acc:o95487]	2956	SEC24B	Measured
			Ranked
			Squared
			Rooted
protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	2910	no value	Measured
			Ranked
			Squared
			Rooted
protein transport protein sec24d (sec24-related protein d). [swissprot;acc:o94855]	2903	SEC24D	Measured
			Ranked
			Squared
			Rooted
protein-tyrosine phosphatase, non-receptor type 11 (ec 3.1.3.48) (protein-tyrosine phosphatase 2c) (ptp-2c) (ptp-1d) (sh-ptp3) (sh- ptp2) (shp-2). [swissprot;acc:q06124]	2789	PTPN11	Measured
			Ranked
			Squared
			Rooted
protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]	2838	DCHS1	Measured
			Ranked
			Squared
			Rooted
protoporphyrinogen oxidase (ec 1.3.3.4) (ppo). [swissprot;acc:p50336]	2934	PPOX	Measured
			Ranked
			Squared
			Rooted
ptd016 protein. [refseq;acc:nm_016125]	3093	no value	Measured
			Ranked
			Squared
			Rooted
putative membrane protein. [refseq;acc:nm_019026]	2935	TMCO1	Measured
			Ranked
			Squared
			Rooted
putative mitochondrial solute carrier; hypothetical protein npd016; putative mitochondrial solute carrier. [refseq;acc:nm_031212]	2891	SLC25A28	Measured
			Ranked
			Squared
			Rooted
putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]	3146	DERL3	Measured
			Ranked
			Squared
			Rooted
	5056		Measured	Low confidence
			Ranked
			Squared
			Rooted
putative tumor suppressor 101f6. [refseq;acc:nm_007022]	3051	CYB561D2	Measured	High confidence
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.