MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	red	Network Comparison Type	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1173 to 1222 of 2060 in total

red  : 0
Network Comparison Type  : Subtracted
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
postsynaptic protein cript; hspc139 protein. [refseq;acc:nm_014171]	3034	CRIPT	Measured
			Ranked
			Squared
			Rooted
potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	2975	KCTD3	Measured
			Ranked
			Squared
			Rooted
prefoldin subunit 4 (protein c-1). [swissprot;acc:q9nqp4]	3130	PFDN4	Measured
			Ranked
			Squared
			Rooted
presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341]	3100	no value	Measured
			Ranked
			Squared
			Rooted
prkca-binding protein (protein kinase c-alpha binding protein) (protein interacting with c kinase 1). [swissprot;acc:q9nrd5]	3143	PICK1	Measured
			Ranked
			Squared
			Rooted
programmed cell death 10; apoptosis-related protein 15. [refseq;acc:nm_007217]	3052	PDCD10	Measured
			Ranked
			Squared
			Rooted
prostate tumor overexpressed gene 1; prostate tumor over expressed gene 1. [refseq;acc:nm_017432]	3106	PTOV1	Measured
			Ranked
			Squared
			Rooted
protease inhibitor 15 preproprotein; 25 kda trypsin inhibitor. [refseq;acc:nm_015886]	2966	PI15	Measured
			Ranked
			Squared
			Rooted
proteasome activator complex subunit 3 (proteasome activator 28-gamma subunit) (pa28gamma) (pa28g) (activator of multicatalytic protease subunit 3) (11s regulator complex gamma subunit) (reg-gamma) (ki nuclear autoantigen). [swissprot;acc:q12920]	2997	PSME3	Measured
			Ranked
			Squared
			Rooted
protein c20orf24 (rab5-interacting protein) (rip5) (pnas-11). [swissprot;acc:q9buv8]	3131	C20orf24	Measured
			Ranked
			Squared
			Rooted
protein c20orf43 (hspc164/hspc169) (ad-007) (cda05). [swissprot;acc:q9by42]	3206	C20orf43	Measured
			Ranked
			Squared
			Rooted
protein c21orf2 (c21orf-humf09g8.5) (yf5/a2). [swissprot;acc:o43822]	2874	C21orf2	Measured
			Ranked
			Squared
			Rooted
protein c6orf55 (dopamine responsive protein drg-1) (my012 protein) (hspc228). [swissprot;acc:q9np79]	3219	VTA1	Measured
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.