MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1112 to 1161 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	green	network_comparison
centaurin beta 2 (cnt-b2). [swissprot;acc:q15057]	2035	CENTB2	Divided	218.919	220.812	1.00865
centaurin beta 5 (cnt-b5). [swissprot;acc:q96p50]	2007	CENTB5	Subtracted			1.893
	2034		Divided			1.00865
centaurin gamma 1. [swissprot;acc:q99490]	1891	CENTG1	Subtracted	220.659	218.452	2.207
	1924		Divided			1.0101
centaurin gamma 2. [swissprot;acc:q9upq3]	1889	CENTG2	Subtracted			2.207
	1922		Divided			1.0101
centaurin gamma 3. [swissprot;acc:q96p47]	1892	CENTG3	Subtracted			2.207
	1925		Divided			1.0101
centromere protein j; centrosomal p4.1-associated protein; lyst-interacting protein lip1; lag-3-associated protein. [refseq;acc:nm_018451]	1317	CENPJ		206.773	202.105	1.0231
	1319		Subtracted			4.668
centromere/kinetochore protein zw10 homolog. [swissprot;acc:o43264]	3167	ZW10	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
cerebral cell adhesion molecule. [refseq;acc:nm_016174]	2508	CEECAM1	Divided	194.349	193.871	1.00247
	2522		Subtracted			0.478
cg9578-like; yeast ypr037w and worm c02c2.6 predicted proteins-like. [refseq;acc:nm_152902]	138	TIPRL		174.667	205.556	30.889
	172		Divided			1.17685
cgi-142; hepatoma-derived growth factor 2. [refseq;acc:nm_016073]	781	no value	Subtracted	231.734	222.222	9.512
	832		Divided			1.0428
cgthba protein (-14 gene protein). [swissprot;acc:q12980]	592	C16orf35	Subtracted	217.67	230.596	12.926
	644		Divided			1.05938
channel associated protein of synapse-110 (chapsyn-110) (discs, large homolog 2). [swissprot;acc:q15700]	2647	DLG2	Subtracted	216.934	216.7	0.234
	2657		Divided			1.00108
chaperone-activity of bc1 complex-like, mitochondrial precursor (chaperone-abc1-like). [swissprot;acc:q8ni60]	1726	CABC1	Subtracted	215.336	212.567	2.769
	1730		Divided			1.01303
choline dehydrogenase. [refseq;acc:nm_018397]	1647	CHDH		217.256	214.149	1.01451
	1654		Subtracted			3.107
choline o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat). [swissprot;acc:p28329]	1936	CHAT		211.632	213.702	2.07
	1967		Divided			1.00978
cholinephosphate cytidylyltransferase a (ec 2.7.7.15) (phosphorylcholine transferase a) (ctp:phosphocholine cytidylyltransferase a) (ct a) (cct a) (cct-alpha). [swissprot;acc:p49585]	189	PCYT1A	Subtracted	241.373	267.352	25.979
	269		Divided			1.10763
cholinephosphate cytidylyltransferase b (ec 2.7.7.15) (phosphorylcholine transferase b) (ctp:phosphocholine cytidylyltransferase b) (ct b) (cct b) (cct-beta). [swissprot;acc:q9y5k3]	195	PCYT1B	Subtracted			25.979
	275		Divided			1.10763
chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0]	139	CHRAC1	Subtracted	287.41	256.835	30.575
	234		Divided			1.11905
chromatin assembly factor 1 subunit c (caf-1 subunit c) (chromatin assembly factor i p48 subunit) (caf-i 48 kda subunit) (caf-ip48) (retinoblastoma binding protein p48) (retinoblastoma-binding protein 4) (rbbp-4) (msi1 protein homolog). [swissprot;acc:q09028]	240	RBBP4	Subtracted	252.39	228.297	24.093
	282		Divided			1.10553
chromatin-specific transcription elongation factor large subunit. [refseq;acc:nm_007192]	838	SUPT16H	Subtracted	237.62	228.762	8.858
	902		Divided			1.03872
chromobox protein homolog 1 (heterochromatin protein 1 homolog beta) (hp1 beta) (modifier 1 protein) (m31) (heterochromatin protein p25). [swissprot;acc:p23197]	2535	CBX1		188.228	188.63	1.00214
	2541		Subtracted			0.402
chromobox protein homolog 3 (heterochromatin protein 1 homolog gamma) (hp1 gamma) (modifier 2 protein) (hech). [swissprot;acc:q13185]	2509	CBX3	Divided	187.902	188.366	1.00247
	2530		Subtracted			0.464
chromobox protein homolog 5 (heterochromatin protein 1 homolog alpha) (hp1 alpha) (antigen p25). [swissprot;acc:p45973]	2505	CBX5	Divided	187.853	188.326	1.00252
	2525		Subtracted			0.473
chromodomain helicase dna binding protein 5. [refseq;acc:nm_015557]	168	CHD5		312	284	28
	335		Divided			1.09859
chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]	158	CHD3	Subtracted			28
	330		Divided			1.09859
chromodomain protein, y chromosome-like isoform a; cdy-like, autosomal; testis-specific chromodomain y-like protein. [refseq;acc:nm_004824]	2553	CDYL		193.12	193.467	1.0018

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.