MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	red	Gene	Rank	Hugo	Value Type	network_comparison	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1075 to 1124 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
nucleoplasmin 3. [swissprot;acc:o75607]	3096	NPM3	Squared
			Rooted
nucleoporin 50 kda (nuclear pore-associated protein 60 kda-like) (pro1146). [swissprot;acc:q9ukx7]	3154	NUP50	Measured
			Ranked
			Squared
			Rooted
nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]	2757	NAP1L1	Measured
			Ranked
			Squared
			Rooted
nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]	2758	NAP1L2	Measured
			Ranked
			Squared
			Rooted
nucleosome assembly protein 1-like 4 (nucleosome assembly protein 2) (nap2). [swissprot;acc:q99733]	3080	no value	Measured
			Ranked
			Squared
			Rooted
origin recognition complex subunit 2. [swissprot;acc:q13416]	3047	ORC2L	Measured
			Ranked
			Squared
			Rooted
origin recognition complex subunit 5. [swissprot;acc:o43913]	2851	ORC5L	Measured
			Ranked
			Squared
			Rooted
orphan nuclear receptor nr5a2 (alpha-1-fetoprotein transcription factor) (hepatocytic transcription factor) (b1-binding factor) (hb1f) (cyp7a promoter binding factor). [swissprot;acc:o00482]	3042	NR5A2	Measured
			Ranked
			Squared
			Rooted
pak1 interacting protein 1; pak1-interacting protein; pak/plc-interacting protein 1. [refseq;acc:nm_017906]	3072	PAK1IP1	Measured
			Ranked
			Squared
			Rooted
pantothenate kinase 4 (ec 2.7.1.33) (pantothenic acid kinase 4) (hpank4). [swissprot;acc:q9nve7]	2883	PANK4	Measured
			Ranked
			Squared
			Rooted
peptide deformylase, mitochondrial precursor (ec 3.5.1.88) (pdf) (polypeptide deformylase). [swissprot;acc:q9hbh1]	2884	PDF	Measured
			Ranked
			Squared
			Rooted
peregrin (bromodomain and phd finger-containing protein 1) (br140 protein). [swissprot;acc:p55201]	2820	no value	Measured
			Ranked
			Squared
			Rooted
pericentrin 1; frount; nucleoporin nup75. [refseq;acc:nm_024844]	3015	NUP85	Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.