MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Network Comparison Type	red	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1008 to 1057 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
network_comparison  : 0
Interaction Map  : High confidence
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type
nadh-ubiquinone oxidoreductase 24 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3). [swissprot;acc:p19404]	2795	NDUFV2	Rooted
nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489]	3081	PTPMT1	Measured
			Ranked
			Squared
			Rooted
nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	2954	NDUFA9	Measured
			Ranked
			Squared
			Rooted
nadh-ubiquinone oxidoreductase 49 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-49kd) (ci-49kd). [swissprot;acc:o75306]	2878	NDUFS2	Measured
			Ranked
			Squared
			Rooted
nanos (fragment). [sptrembl;acc:q8wy41]	2803	no value	Measured
			Ranked
			Squared
			Rooted
neuromedin u receptor 2. [refseq;acc:nm_020167]	2991	NMUR2	Measured
			Ranked
			Squared
			Rooted
ngd5 protein homolog (cgi-53). [swissprot;acc:q9y366]	3133	IFT52	Measured
			Ranked
			Squared
			Rooted
nipsnap1 protein. [swissprot;acc:q9bpw8]	2770	NIPSNAP1	Measured
			Ranked
			Squared
			Rooted
nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323]	2918	GBAS	Measured
			Ranked
			Squared
			Rooted
nk6 transcription factor related, locus 2; nk homeobox family 6, b; glial and testis-specific homeobox protein; homeobox 6b. [refseq;acc:nm_177400]	2909	NKX6-2	Measured
			Ranked
			Squared
			Rooted
nov protein homolog precursor (novh) (nephroblastoma overexpressed gene protein homolog). [swissprot;acc:p48745]	2970	NOV	Measured
			Ranked
			Squared
			Rooted
nuclear autoantigen sp-100 (speckled 100 kda) (nuclear dot-associated sp100 protein) (lysp100b). [swissprot;acc:p23497]	3184	SP100	Measured
			Ranked
			Squared
			Rooted
nuclear factor related to kappa b binding protein. [refseq;acc:nm_006165]	2823	NFRKB	Measured
			Ranked
			Squared
			Rooted
nuclear pore complex protein nup214 (nucleoporin nup214) (214 kda nucleoporin) (can protein). [swissprot;acc:p35658]	3008	NUP214	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.