MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1008 to 1057 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	2504	no value	Squared	Subtracted	12429.9	13562.6	1132.7
60s ribosomal protein l15. [swissprot;acc:p39030]	577	RPL15	Ranked		217.862	230.978	13.116
	604			Divided			1.0602
	1089		Squared		17766.4	20351.7	1.14552
	1546			Subtracted			2585.3
	2238		Rooted	Divided	59.1718	57.9477	1.02112
	2312			Subtracted			1.2241
	2530		Measured		4888.72	5006.1	117.38
	2532			Divided			1.02401
60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	200	no value	Ranked	Subtracted	241.808	267.335	25.527
	281			Divided			1.10557
	343		Rooted		50.3169	45.4333	1.10749
	590			Subtracted			4.8836
	1894		Measured	Divided	3598.08	3384.59	1.06308
	2212		Squared		12360.4	13390.2	1.08331
	2362		Measured	Subtracted	3598.08	3384.59	213.49
	2538		Squared		12360.4	13390.2	1029.8
60s ribosomal protein l18. [swissprot;acc:q07020]	411	RPL18	Ranked		237.109	254.667	17.558
	485			Divided			1.07405
	969		Rooted		52.9804	50.0947	1.0576
	1188			Subtracted			2.8857
	1618		Squared	Divided	15399.5	17067.9	1.10834
	2244			Subtracted			1668.4
	2694		Measured	Divided	4113.79	4095.53	1.00446
	2734			Subtracted			18.26
60s ribosomal protein l18a. [swissprot;acc:q02543]	770	no value	Rooted	Divided	55.6817	59.3786	1.06639
	806		Measured		4708.61	5226.71	1.11003
	819		Ranked	Subtracted	234.025	224.958	9.067
	860			Divided			1.04031
	906		Rooted	Subtracted	55.6817	59.3786	3.6969
	1098		Measured		4708.61	5226.71	518.1
	1128		Squared	Divided	18854.4	21540.4	1.14246
	1477			Subtracted			2686
60s ribosomal protein l19. [swissprot;acc:p14118]	245	RPL19	Ranked		240.73	264.729	23.999
	319			Divided			1.09969
	435		Rooted		50.832	46.3081	1.09769
	690			Subtracted			4.5239
	2054		Squared	Divided	12769	13918.3	1.09001
	2136		Measured		3687.49	3499.2	1.05381
	2401			Subtracted			188.29
	2491		Squared		12769	13918.3	1149.3
60s ribosomal protein l21. [swissprot;acc:p46778]	1019	no value	Ranked		223.958	217.263	6.695
	1051		Rooted	Divided	60.1366	63.2237	1.05133
	1054		Ranked		223.958	217.263	1.03082
	1111		Rooted	Subtracted	60.1366	63.2237	3.0871
	1510		Measured	Divided	5546.11	5957.99	1.07426
	1663			Subtracted			411.88
	2308		Squared		25226.2	26738.9	1512.7
	2453			Divided			1.05997
60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	2034			Subtracted	38544.3	36568.4	1975.9

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.