MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Network Comparison Type	Gene	description	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1001 to 1050 of 2061 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
3006	dgcr8 protein (digeorge syndrome critical region 8). [swissprot;acc:q8wyq5]	DGCR8	Measured
			Ranked
			Squared
			Rooted
3007	glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530]	YEATS4	Measured
			Ranked
			Squared
			Rooted
3008	nuclear pore complex protein nup214 (nucleoporin nup214) (214 kda nucleoporin) (can protein). [swissprot;acc:p35658]	NUP214	Measured
			Ranked
			Squared
			Rooted
3009	cytochrome c oxidase polypeptide vib (ec 1.9.3.1) (aed). [swissprot;acc:p14854]	COX6B1	Measured
			Ranked
			Squared
			Rooted
3010	uroporphyrinogen decarboxylase (ec 4.1.1.37) (uro-d) (upd). [swissprot;acc:p06132]	UROD	Measured
			Ranked
			Squared
			Rooted
3011	dna replication licensing factor mcm8 (minichromosome maintenance 8). [swissprot;acc:q9uja3]	MCM8	Measured
			Ranked
			Squared
			Rooted
3012	small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678]	SNRPB	Measured
			Ranked
			Squared
			Rooted
3013	major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	CENPB	Measured
			Ranked
			Squared
			Rooted
3014	mitochondrial deoxynucleotide carrier (mitochondrial uncoupling protein 1). [swissprot;acc:q9hc21]	SLC25A19	Measured
			Ranked
			Squared
			Rooted
3015	pericentrin 1; frount; nucleoporin nup75. [refseq;acc:nm_024844]	NUP85	Measured
			Ranked
			Squared
			Rooted
3016	mitochondrial ribosomal protein s7; 30s ribosomal protein s7 homolog. [refseq;acc:nm_015971]	MRPS7	Measured
			Ranked
			Squared
			Rooted
3017	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	LRRFIP1	Measured
			Ranked
			Squared
			Rooted
3018	cysteine-rich secretory protein-1 precursor (crisp-1) (acidic epididymal glycoprotein homolog) (aeg-like protein) (arp). [swissprot;acc:p54107]	CRISP1	Measured
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.