MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Filtered	Interaction Map	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 1948 in total

Network Comparison Type  : Subtracted
Filtered  : 0
Interaction Map  : High confidence
red  : 0

Rank	description	Value Type	network_comparison	green
13	cab2. [refseq;acc:nm_033419]	Rooted	13.1909	13.1909
25	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]		10.4403	10.4403
30	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		9.43398	9.43398
31	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
32	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
52	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]		7.68115	7.68115
65	sedlin. [swissprot;acc:o14582]		6.55744	6.55744
66	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
116	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]		4.24264	4.24264
185	cab2. [refseq;acc:nm_033419]	Measured	174	174
265	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]		109	109
289	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		89	89
290	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
291	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
342	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]		59	59
376	sedlin. [swissprot;acc:o14582]		43	43
377	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
402	cab2. [refseq;acc:nm_033419]	Squared	7.16592	7.16592
428	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Measured	18	18
429	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]	Squared	2.81207	2.81207
437	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		1.87479	1.87479
438	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
439	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
450	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]		0.823905	0.823905
457	sedlin. [swissprot;acc:o14582]		0.437633	0.437633
458	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
470	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]		0.0766864	0.0766864
494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured	0	0
		Squared
		Rooted
495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured
		Squared
		Rooted
496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured
		Squared
		Rooted
497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured
		Squared
		Rooted
498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured
		Squared
		Rooted
499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Measured
		Squared
		Rooted
500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	Measured
		Squared
		Rooted
501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Measured
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.