MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2113 to 2162 of 6456 in total

Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Network Comparison Type	red	green	network_comparison
1057	mitochondrial translational release factor 1-like. [refseq;acc:nm_019041]	Subtracted	5168.01	5696.12	528.11
	tata element modulatory factor (tmf). [swissprot;acc:p82094]	Divided	5412.23	5913.4	1.0926
1058	protein-tyrosine phosphatase, non-receptor type 2 (ec 3.1.3.48) (t- cell protein-tyrosine phosphatase) (tcptp). [swissprot;acc:p17706]	Subtracted	6275.86	6803.95	528.09
	scy1-like 1; telomerase regulation-associated protein; ht019 protein; telomerase regulation-associated protein; n-terminal kinase-like protein; teratoma-associated tyrosine kinase; n-terminal kinase-like. [refseq;acc:nm_020680]	Divided	5412.23	5913.4	1.0926
1059	tgf beta-inducible nuclear protein 1; hairy cell leukemia protein 1. [refseq;acc:nm_014886]	Subtracted	3853.64	4379.71	526.07
	tubulin-specific chaperone c (tubulin-folding cofactor c) (cfc). [swissprot;acc:q15814]	Divided	5719.01	6248.6	1.0926
1060	polyadenylate-binding protein 3 (poly(a)-binding protein 3) (pabp 3) (testis-specific poly(a)-binding protein). [swissprot;acc:q9h361]	Subtracted	5791.05	6316.61	525.56
	putative acyl-coa thioester hydrolase cgi-16 (ec 3.1.2.-). [swissprot;acc:q9y305]	Divided	5719.01	6248.6	1.0926
1061	hskin17 protein. [refseq;acc:nm_012311]	Subtracted	5791.05	6316.61	525.56
	nuclear pore complex protein nup98 (nucleoporin nup98) (98 kda nucleoporin). [swissprot;acc:p52948]	Divided	5412.23	5913.4	1.0926
1062	ammecr1 protein. [refseq;acc:nm_015365]
	carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [swissprot;acc:p43155]	Subtracted	5791.05	6316.61	525.56
1063	mrna-associated protein mrnp 41 (rae1 protein homolog). [swissprot;acc:p78406]	Divided	5412.23	5913.4	1.0926
	polyadenylate-binding protein 4 (poly(a)-binding protein 4) (pabp 4) (inducible poly(a)-binding protein) (ipabp) (activated-platelet protein-1) (app-1). [swissprot;acc:q13310]	Subtracted	5791.05	6316.61	525.56
1064	dead-box protein. [refseq;acc:nm_018665]	Divided	5719.01	6248.6	1.0926
	polyadenylate-binding protein 1 (poly(a)-binding protein 1) (pabp 1). [swissprot;acc:p11940]	Subtracted	5791.05	6316.61	525.56
1065	dehydrodolichyl diphosphate synthase. [refseq;acc:nm_024887]		6350.81	6874.88	524.07
	dna-(apurinic or apyrimidinic site) lyase (ec 4.2.99.18) (ap endonuclease 1) (apex nuclease) (apen) (ref-1 protein). [swissprot;acc:p27695]	Divided	6393.81	6984.94	1.09245
1066	junction plakoglobin (desmoplakin iii). [swissprot;acc:p14923]	Subtracted	5732.73	6256.63	523.9
	leucyl-trna synthetase. [refseq;acc:nm_020117]	Divided	5417.06	5917.79	1.09244
1067	probable leucyl-trna synthetase, mitochondrial precursor (ec 6.1.1.4) (leucine--trna ligase) (leurs). [swissprot;acc:q15031]		5417.07		1.09243
	tax interaction protein 1. [refseq;acc:nm_014604]	Subtracted	5732.73	6256.63	523.9
1068	argininosuccinate lyase (ec 4.3.2.1) (arginosuccinase) (asal). [swissprot;acc:p04424]		5857.48	6380.4	522.92
	exocyst complex component sec15a. [swissprot;acc:q8tag9]	Divided	6201.54	6774.35	1.09237
1069	elongation factor 2 (ef-2). [swissprot;acc:p13639]		5494.73	6001.08	1.09215
	glutamate carboxypeptidase-like protein 2 precursor. [swissprot;acc:q96kn2]	Subtracted	6251.32	6774.12	522.8
1070	metabotropic glutamate receptor 2 precursor (mglur2). [swissprot;acc:q14416]	Divided	5494.73	6001.08	1.09215
	thymidylate kinase (ec 2.7.4.9) (dtmp kinase). [swissprot;acc:p23919]	Subtracted	6042.31	6565.03	522.72
1071	40s ribosomal protein s30. [swissprot;acc:q05472]		5893.97	6416.07	522.1
	metabotropic glutamate receptor 3 precursor (mglur3). [swissprot;acc:q14832]	Divided	5494.73	6001.08	1.09215
1072	electron transfer flavoprotein beta-subunit (beta-etf). [swissprot;acc:p38117]	Subtracted	7794.41	8316.04	521.63
	prefoldin subunit 3 (von hippel-lindau binding protein 1) (vhl binding protein-1) (vbp-1) (hibbj46). [swissprot;acc:q15765]	Divided	5207.39	5687.2	1.09214
1073	dimethylaniline monooxygenase [n-oxide forming] 5 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 5) (fmo 5) (dimethylaniline oxidase 5). [swissprot;acc:p49326]	Subtracted	5364.3	5885.48	521.18
	prefoldin subunit 2 (hspc231). [swissprot;acc:q9uhv9]	Divided	5207.39	5687.2	1.09214
1074	putative dimethylaniline monooxygenase [n-oxide forming] 6 (ec 1.14.13.8) (flavin-containing monooxygenase 6) (fmo 6) (dimethylaniline oxidase 6). [swissprot;acc:o60774]	Subtracted	5364.3	5885.48	521.18
	uxt protein (ubiquitously expressed transcript protein) (hspc024). [swissprot;acc:q9ubk9]	Divided	5207.39	5687.2	1.09214
1075	eukaryotic translation initiation factor 3 subunit 9 (eif-3 eta) (eif3 p116) (eif3 p110) (eif3b). [swissprot;acc:p55884]	Subtracted	4359.82	4880.99	521.17
	phosphatidate cytidylyltransferase 1 (ec 2.7.7.41) (cdp-diglyceride synthetase 1) (cdp-diglyceride pyrophosphorylase 1) (cdp- diacylglycerol synthase 1) (cds 1) (ctp:phosphatidate cytidylyltransferase 1) (cdp-dag synthase 1) (cdp-dg synthetase 1). [swissprot;acc:q92903]	Divided	6441.56	7034.86	1.09211
1076	ethanolamine-phosphate cytidylyltransferase (ec 2.7.7.14) (phosphorylethanolamine transferase) (ctp:phosphoethanolamine cytidylyltransferase). [swissprot;acc:q99447]	Subtracted	4565.34	5085.92	520.58
	solute carrier family 13, member 4 (na+/sulfate cotransporter sut-1). [swissprot;acc:q9ukg4]	Divided	6439.63	7032.19	1.09202
1077	myosin light chain 1, skeletal muscle isoform (mlc1f) (a1 catalytic) (alkali). [swissprot;acc:p05976]	Subtracted	4565.34	5085.92	520.58
	solute carrier family 13, member 3 (sodium-dependent high-affinity dicarboxylate transporter 2) (na(+)/dicarboxylate cotransporter 3) (nadc-3) (hnadc3). [swissprot;acc:q8wwt9]	Divided	6439.66	7032.22	1.09202
1078	myosin light chain 1, slow-twitch muscle b/ventricular isoform (mlc1sb) (alkali). [swissprot;acc:p08590]	Subtracted	4565.34	5085.92	520.58
	solute carrier family 13, member 1 (renal sodium/sulfate cotransporter) (na(+)/sulfate cotransporter) (hnasi-1). [swissprot;acc:q9bzw2]	Divided	6439.63	7032.19	1.09202
1079	nadh-ubiquinone oxidoreductase 13 kda-a subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-a) (ci-13kd-a). [swissprot;acc:o75380]	Subtracted	4565.34	5085.92	520.58
	solute carrier family 13, member 2 (renal sodium/dicarboxylate cotransporter) (na(+)/dicarboxylate cotransporter 1) (nadc-1). [swissprot;acc:q13183]	Divided	6439.66	7032.22	1.09202
1080	myosin light chain 1, slow-twitch muscle a isoform (mlc1sa) (alkali). [swissprot;acc:p14649]	Subtracted	4565.34	5085.92	520.58
	secretory carrier-associated membrane protein 2. [swissprot;acc:o15127]	Divided	6439.3	7031.73	1.092
1081	myosin light chain 1, embryonic muscle/atrial isoform (pro1957). [swissprot;acc:p12829]	Subtracted	4565.34	5085.92	520.58
	secretory carrier-associated membrane protein 3. [swissprot;acc:o14828]	Divided	6439.3	7031.73	1.092

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.