MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Value Type	Filtered	green	Gene	Rank	description	Interaction Map	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 29840 in total

Value Type  : Measured
Filtered  : 0
Interaction Map  : High confidence

green	Rank	description	Network Comparison Type	network_comparison	red
0	88	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	Subtracted	364	364
	206	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]		154	154
	207	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	316	ero1-like. [refseq;acc:nm_014584]		82	82
	338	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]		60	60
	386	dok-like protein. [refseq;acc:nm_024872]		35	35
	429	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]		18	18
	494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		0	0
	495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
	496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
	497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
	498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
	499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
	500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
	501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
	502	brca1 associated protein. [refseq;acc:nm_006768]
0.00001	1	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	Divided	36400000	364
	20	ero1-like. [refseq;acc:nm_014584]		8200000	82
	22	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]		6000000	60
	31	dok-like protein. [refseq;acc:nm_024872]		3500000	35
	65	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]		1800000	18
	95	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]		15400000	154
	96	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		1	0.00001
	495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
	496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]
	497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
	498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]
	499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
	500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]
	501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
	502	brca1 associated protein. [refseq;acc:nm_006768]
5.56738	11	serpin b12. [swissprot;acc:q96p63]		35.8425	199.549
	168		Subtracted	193.982
5.71669	12	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]	Divided	34.8539	199.249
	169		Subtracted	193.532
6.50325	14	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	Divided	20.0687	130.512
	258		Subtracted	124.009
11.5	190	protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]	Divided	1.21739	14
	489		Subtracted	2.5
14.3333	121	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	Divided	1.3721	19.6667
	460		Subtracted	5.3334
15	16	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]	Divided	15	1
	443		Subtracted	14
17.6611	21	syntaxin 10 (syn10). [swissprot;acc:o60499]	Divided	6.73106	118.878
	269		Subtracted	101.217
18	64	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Divided	1800000	0.00001
	428		Subtracted	18	0
19	195	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]	Divided	1.21053	23
	464		Subtracted	4

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.