MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 1921 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Value Type	Filtered
494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured	0
		Squared
		Rooted
495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured
		Squared
		Rooted
496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured
		Squared
		Rooted
497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured
		Squared
		Rooted
498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured
		Squared
		Rooted
499	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Measured
		Squared
		Rooted
500	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	Measured
		Squared
		Rooted
501	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Measured
		Squared
		Rooted
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Ranked
502	brca1 associated protein. [refseq;acc:nm_006768]	Measured
		Ranked
		Squared
		Rooted
2756	3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Measured	1
		Ranked
		Squared
		Rooted
2757	nucleosome assembly protein 1-like 1 (nap-1 related protein). [swissprot;acc:p55209]	Measured
		Ranked
		Squared
		Rooted
2758	nucleosome assembly protein 1-like 2 (brain-specific protein, x- linked). [swissprot;acc:q9ulw6]	Measured
		Ranked
		Squared
		Rooted
2759	retinoic acid receptor rxr-alpha. [swissprot;acc:p19793]	Measured
		Ranked
		Squared
		Rooted
2760	t-cell acute lymphocytic leukemia-2 protein (tal-2 protein). [swissprot;acc:q16559]	Measured
		Ranked
		Squared
		Rooted
2761	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.