MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	description	Value Type	Filtered	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red

Results: HTML CSV LaTeX

Showing element 451 to 500 of 9634 in total

Value Type  : Ranked
Network Comparison Type  : Divided

description	Filtered	Rank	network_comparison	Interaction Map	green	red
abhydrolase domain containing protein 2 (protein phps1-2). [swissprot;acc:p08910]	1	1935	1.00995	High confidence	216.279	218.43
		2521	1.01814	Low confidence	197.494	201.076
abl-interactor 2; abl-interacting protein 1 (sh3-containing protein); abl binding protein 3; arg protein tyrosine kinase-binding protein; abl-interactor protein 2b; similar to spectrin sh3 domain binding protein 1. [refseq;acc:nm_005759]		779	1.02662		197.229	202.48
		1845	1.01106	High confidence	214.702	217.077
abl-philin 2. [refseq;acc:nm_032327]	0	389	1.08416	Low confidence	17688	16315
	1	3025	1.01668		199.029	202.348
acetyl-coa acetyltransferase, mitochondrial precursor (ec 2.3.1.9) (acetoacetyl-coa thiolase) (t2). [swissprot;acc:p24752]		2259	1.01886		196.214	199.914
		2306	1.00508	High confidence	192.544	191.571
acetyl-coa carboxylase 1 (ec 6.4.1.2) (acc-alpha) [includes: biotin carboxylase (ec 6.3.4.14)]. [swissprot;acc:q13085]		2143	1.01914	Low confidence	193.896	197.608
		2319	1.00492	High confidence	195.8	194.842
acetyl-coa carboxylase 2 (ec 6.4.1.2) (acc-beta) [includes: biotin carboxylase (ec 6.3.4.14)]. [swissprot;acc:o00763]		2144	1.01914	Low confidence	193.891	197.602
		2315	1.00494	High confidence	195.787	194.825
acetyl-coenzyme a acetyltransferase 2; acetoacetyl coenzyme a thiolase. [refseq;acc:nm_005891]		4559	1.00798	Low confidence	200.117	201.714
acetyl-coenzyme a synthetase, cytoplasmic (ec 6.2.1.1) (acetate--coa ligase) (acyl-activating enzyme) (acetyl-coa synthetase) (acs) (acecs). [swissprot;acc:q9nr19]		2039	1.00861	High confidence	192.191	190.551
		2376	1.01855	Low confidence	196.211	199.85
acetyl-coenzyme a transporter. [refseq;acc:nm_004733]		2713	1.01752		198.156	201.627
acid ceramidase precursor (ec 3.5.1.23) (acylsphingosine deacylase) (n-acylsphingosine amidohydrolase) (ac) (putative 32 kda heart protein) (php32). [swissprot;acc:q13510]		1421	1.02084	High confidence	211.391	207.076
		2275	1.01882	Low confidence	199.972	203.735
acid sphingomyelinase-like phosphodiesterase 3a (ec 3.1.4.-) (asm-like phosphodiesterase 3a) (fragment). [swissprot;acc:q92484]		2956	1.01691		198.377	201.732
acid sphingomyelinase-like phosphodiesterase 3b precursor (ec 3.1.4.-) (asm-like phosphodiesterase 3b). [swissprot;acc:q92485]		2960
acidic 82 kda protein mrna. [refseq;acc:nm_014597]		4677	1.00595		201.278	202.475
acidic leucine-rich nuclear phosphoprotein 32 family member a (potent heat-stable protein phosphatase 2a inhibitor i1pp2a) (hla-dr associated protein i) (phapi) (acidic nuclear phosphoprotein pp32) (cerebellar leucine rich acidic nuclear protein). [swissprot;acc:p39687]		569	1.03088		200.275	206.46
acidic leucine-rich nuclear phosphoprotein 32 family member b (phapi2 protein) (silver-stainable protein ssp29) (acidic protein rich in leucines). [swissprot;acc:q92688]		572
acidic leucine-rich nuclear phosphoprotein 32 family member c (tumorigenic protein pp32r1). [swissprot;acc:o43423]	0	270	1.13916		15399	17542
	1	567	1.03088		200.275	206.46
acidic leucine-rich nuclear phosphoprotein 32 family member d (tumorigenic protein pp32r2). [swissprot;acc:o95626]	0	271	1.13916		15399	17542
	1	570	1.03088		200.275	206.46
aconitate hydratase, mitochondrial precursor (ec 4.2.1.3) (citrate hydro-lyase) (aconitase). [swissprot;acc:q99798]		1299	1.02237		195.959	200.342
acrc protein; putative nuclear protein. [refseq;acc:nm_052957]	0	21	1.68236	High confidence	10621.4	6313.38
		322	1.10947	Low confidence	11238.6	10129.7
	1	2101	1.00737	High confidence	213.27	211.71
		2308	1.01869	Low confidence	197.572	201.265
actin binding lim protein 2. [refseq;acc:nm_032432]		660	1.0577	High confidence	216.576	229.072
		820	1.02612	Low confidence	203.181	208.488
actin, alpha cardiac. [swissprot;acc:p04270]		3962	1.01209		198.479	200.879
actin, aortic smooth muscle (alpha-actin 2). [swissprot;acc:p03996]	0	668	1.02226		11418.9	11170.2
	1	3964	1.01209		198.477	200.877
actin, cytoplasmic 2 (gamma-actin). [swissprot;acc:p02571]	0	382	1.03848	High confidence	10061.8	10449
		829	1.00149	Low confidence	11085.2	11101.7
	1	1529	1.01751	High confidence	213.031	216.762
		3630	1.01418	Low confidence	197.828	200.633
actin, gamma-enteric smooth muscle (alpha-actin 3). [swissprot;acc:p12718]		3961	1.01209		198.477	200.877
actin-binding lim protein 1 isoform a; lim actin-binding protein 1; limatin; actin-binding lim protein. [refseq;acc:nm_002313]		668	1.0577	High confidence	216.576	229.072
		822	1.02612	Low confidence	203.181	208.488
actin-like protein 2 (actin-related protein 2). [swissprot;acc:o15142]		2626	1.00135	High confidence	225.195	224.891
		3653	1.01403	Low confidence	198.345	201.127
actin-like protein 3 (actin-related protein 3) (actin-2). [swissprot;acc:p32391]		426	1.03512		198.528	205.501
		2631	1.00135	High confidence	225.195	224.891
actin-related protein 2/3 complex subunit 1a (sop2-like protein). [swissprot;acc:q92747]		727	1.02743	Low confidence	196.189	201.571
		2634	1.00135	High confidence	225.195	224.891

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.