MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	description	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 801 to 850 of 66312 in total

Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	red	green	network_comparison
28s ribosomal protein s26, mitochondrial precursor (mrp-s26) (mrp- s13). [swissprot;acc:q9byn8]	2037	MRPS26	Rooted	Subtracted	High confidence	64.5014	66.1778	1.6764
	2071		Measured	Divided		6437.24	6797.24	1.05592
	2082		Rooted			64.5014	66.1778	1.02599
	2449		Squared			33026.7	35032	1.06072
	2617				Low confidence	43757.4	42162.6	1.03782
	2673		Ranked	Subtracted	High confidence	214.893	215.108	0.215
	2675			Divided				1.001
	2715		Squared	Subtracted	Low confidence	43757.4	42162.6	1594.8
28s ribosomal protein s9, mitochondrial precursor (mrp-s9). [swissprot;acc:p82933]	340	MRPS9	Ranked		High confidence	239.75	260.544	20.794
	407			Divided				1.08673
	659		Rooted			51.7081	47.9816	1.07767
	901			Subtracted				3.7265
	1662		Squared	Divided		13992.7	15480.4	1.10632
	2313			Subtracted				1487.7
	2530		Measured	Divided		3880.5	3788.42	1.02431
	2593			Subtracted				92.08
	2844		Squared	Divided	Low confidence	42943	41427.9	1.03657
	3063			Subtracted				1515.1
	3986		Measured	Divided		7621.65	7792.73	1.02245
	4226			Subtracted				171.08
	4585		Rooted	Divided		69.8928	71.3675	1.0211
	4610			Subtracted				1.4747
	4991		Ranked			206.266	206.342	0.076
	4992			Divided				1.00037
3 beta-hydroxy-delta 5-c27-steroid oxidoreductase. [refseq;acc:nm_025193]	1079	HSD3B7	Squared			44737.4	42724.1	1.04712
	1256			Subtracted				2013.3
	1667		Ranked	Divided		197.872	193.866	1.02066
	1737			Subtracted				4.006
	2485		Rooted			73.0199	75.4487	2.4288
	2627			Divided				1.03326
	3147		Measured		High confidence	0.00001	0.00001	1
				Subtracted		0	0	0
			Ranked	Divided		0.00001	0.00001	1
				Subtracted		0	0	0
			Squared	Divided		0.00001	0.00001	1
				Subtracted		0	0	0
			Rooted	Divided		0.00001	0.00001	1
				Subtracted		0	0	0
	3407		Measured		Low confidence	8082.12	8292.57	210.45
	3493			Divided				1.02604
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	1073	no value	Squared			44737.4	42724.1	1.04712
	1252			Subtracted				2013.3
	1663		Ranked	Divided		197.872	193.866	1.02066
	1733			Subtracted				4.006
	2480		Rooted			73.0199	75.4487	2.4288
	2622			Divided				1.03326
	2756		Measured		High confidence	0.00001	0.00001	1
				Subtracted		0	0	0
			Ranked	Divided		0.00001	0.00001	1
				Subtracted		0	0	0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.