MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	green	Value Type	Filtered	Interaction Map	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 9634 in total

Value Type  : Ranked
Network Comparison Type  : Divided

description	Rank	green	Filtered	Interaction Map	network_comparison	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	18	245.247	1	High confidence	1.32082	185.678
	242	13895.8	0		1.09822	15260.6
	629	13590.3		Low confidence	1.02915	13205.3
	4130	201.5	1		1.01062	199.383
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	1038	181.041		High confidence	1.03148	186.741
	1328	194.038		Low confidence	1.02218	198.342
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	1032	180.943		High confidence	1.03162	186.664
	1322	194.014		Low confidence	1.0222	198.322
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	588	185.859			1.03039	191.507
	1048	182.308		High confidence	1.031	187.96
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	637	186.751		Low confidence	1.029	192.166
	1043	182.137		High confidence	1.03128	187.834
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	3423	196.707		Low confidence	1.01523	199.702
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	3126	0.00001		High confidence	1	0.00001
	3585	199.628		Low confidence	1.01447	202.517
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	1963	213.703		High confidence	1.00978	211.633
	2659	196.574		Low confidence	1.0177	200.053
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	1873	199.455			1.01985	203.414
	2922	0.00001		High confidence	1	0.00001
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704]	4255	200.395		Low confidence	1.00954	202.306
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	2076	194.83			1.01928	198.587
	2439	221.425		High confidence	1.00337	220.681
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	2864	197.043		Low confidence	1.01713	200.418
	3088	0.00001		High confidence	1	0.00001
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	2108	194.902		Low confidence	1.01923	198.65
	2396	221.51		High confidence	1.00375	220.683
14.5 kda translational inhibitor protein (p14.5) (uk114 antigen homolog). [swissprot;acc:p52758]	1044	196.966		Low confidence	1.02415	201.723
	2366	202.529		High confidence	1.00407	203.353
15 kda selenoprotein precursor. [swissprot;acc:o60613]	1948	212.432			1.00984	214.522
	4465	201.104		Low confidence	1.00907	202.928
15-hydroxyprostaglandin dehydrogenase [nad(+)] (ec 1.1.1.141) (pgdh). [swissprot;acc:p15428]	2855	0.00001		High confidence	1	0.00001
	4126	195.778		Low confidence	1.01062	197.858
16.7kd protein. [refseq;acc:nm_016139]	3267	195.864			1.01575	198.949
17 beta-hydroxysteroid dehydrogenase. [sptrembl;acc:q13034]	1051	217.998		High confidence	1.03097	211.449
	1803	195.655		Low confidence	1.02012	199.592
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	627	10050.9	0		1.02953	10347.7
	2142	192.884	1		1.01915	196.577
2,4-dienoyl coa reductase 2, peroxisomal; peroxisomal 2,4-dienoyl-coa reductase. [refseq;acc:nm_020664]	3846	198.422			1.01306	201.014
2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor (ec 2.4.1.45) (udp-galactose-ceramide galactosyltransferase) (ceramide udp-galactosyltransferase) (cerebroside synthase). [swissprot;acc:q16880]	4455	205.097			1.00928	207
2-hydroxyphytanoyl-coa lyase (ec 4.1.-.-) (2-hpcl) (hspc279). [swissprot;acc:q9uj83]	941	201.99			1.02493	207.026
	2007	222.969		High confidence	1.00919	225.019
2-oxoglutarate dehydrogenase e1 component, mitochondrial precursor (ec 1.2.4.2) (alpha-ketoglutarate dehydrogenase). [swissprot;acc:q02218]	994	196.729		Low confidence	1.02457	201.562
	1160	214.041		High confidence	1.02633	208.55
2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (ec 1.2.4.4) (branched-chain alpha-keto acid dehydrogenase e1 component alpha chain) (bckdh e1-alpha). [swissprot;acc:p12694]	1484	202.726			1.0191	198.927
	4541	201.202		Low confidence	1.00806	202.824
2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor (ec 1.2.4.4) (branched-chain alpha-keto acid dehydrogenase e1 component beta chain) (bckdh e1-beta). [swissprot;acc:p21953]	1389	213.875		High confidence	1.02148	218.47
	1439	198.891		Low confidence	1.0217	203.206
20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	183	198.011		High confidence	1.153	228.306
	276	191.474		Low confidence	1.04421	199.939
25 kda brain-specific protein (p25-alpha). [swissprot;acc:o94811]	1085	199.188			1.02382	203.933

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.