MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Value Type	green	Gene	Network Comparison Type	Interaction Map	Filtered	red	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 12912 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Value Type	green	red	network_comparison
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	306	Ranked	266.673	242.153	1.10126
	387	Rooted	45.6718	50.3345	1.10209
	2003	Squared	13562.6	12429.9	1.09113
	2074	Measured	3423.89	3614.91	1.05579
60s ribosomal protein l15. [swissprot;acc:p39030]	604	Ranked	230.978	217.862	1.0602
	1089	Squared	20351.7	17766.4	1.14552
	2238	Rooted	57.9477	59.1718	1.02112
	2532	Measured	5006.1	4888.72	1.02401
60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	281	Ranked	267.335	241.808	1.10557
	343	Rooted	45.4333	50.3169	1.10749
	1894	Measured	3384.59	3598.08	1.06308
	2212	Squared	13390.2	12360.4	1.08331
60s ribosomal protein l18. [swissprot;acc:q07020]	485	Ranked	254.667	237.109	1.07405
	969	Rooted	50.0947	52.9804	1.0576
	1618	Squared	17067.9	15399.5	1.10834
	2694	Measured	4095.53	4113.79	1.00446
60s ribosomal protein l18a. [swissprot;acc:q02543]	770	Rooted	59.3786	55.6817	1.06639
	806	Measured	5226.71	4708.61	1.11003
	860	Ranked	224.958	234.025	1.04031
	1128	Squared	21540.4	18854.4	1.14246
60s ribosomal protein l19. [swissprot;acc:p14118]	319	Ranked	264.729	240.73	1.09969
	435	Rooted	46.3081	50.832	1.09769
	2054	Squared	13918.3	12769	1.09001
	2136	Measured	3499.2	3687.49	1.05381
60s ribosomal protein l21. [swissprot;acc:p46778]	1051	Rooted	63.2237	60.1366	1.05133
	1054	Ranked	217.263	223.958	1.03082
	1510	Measured	5957.99	5546.11	1.07426
	2453	Squared	26738.9	25226.2	1.05997
60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	2205	Ranked	200.413	199.129	1.00645
	2530	Squared	36568.4	38544.3	1.05403
	2667	Rooted	72.5201	72.1844	1.00465
	2673	Measured	7741.14	7780.98	1.00515
60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	293	Ranked	265.717	240.782	1.10356
	384	Rooted	46.0607	50.7723	1.10229
	1838	Squared	13887.8	12666.8	1.09639
	2115	Measured	3482.34	3672.49	1.0546
60s ribosomal protein l23a. [swissprot;acc:p29316]	323	Ranked	265.945	241.884	1.09947
	424	Rooted	45.9373	50.4703	1.09868
	1950	Squared	13806.3	12632.4	1.09293
	2175	Measured	3463.88	3642.13	1.05146
60s ribosomal protein l24 (l30). [swissprot;acc:p38663]	420	Squared	37652.3	30924.3	1.21756
	727	Measured	7911.25	7087.23	1.11627
	1128	Rooted	73.3177	69.8977	1.04893
	1767	Ranked	198.86	201.288	1.01221
60s ribosomal protein l26. [swissprot;acc:q02877]	302		267.008	242.326	1.10185
	374	Rooted	45.5599	50.2549	1.10305
	1997	Squared	13513	12380.1	1.09151
	2051	Measured	3409.48	3601.97	1.05646
60s ribosomal protein l28. [swissprot;acc:p46779]	1506	Rooted	65.4287	63.0816	1.03721
	1548	Measured	6423.52	5987.29	1.07286

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.