MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	Filtered	description	Value Type	Network Comparison Type	green	Interaction Map	red	network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 9634 in total

Value Type  : Measured
Network Comparison Type  : Divided

Rank	Filtered	description	green	Interaction Map	red	network_comparison
26	0	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]	662	High confidence	153	4.3268
		glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]	47	Low confidence	143	3.04255
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6]	892.67	High confidence	1833.01	2.0534
		sperm associated antigen 7. [refseq;acc:nm_004890]	19280.8	Low confidence	23318	1.20939
27	0	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	35.5		105.5	2.97183
		phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086]	139	High confidence	570	4.10072
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	895.134		1834.33	2.04922
		protein kinase, interferon-inducible double stranded rna dependent activator; protein activator of the interferon-induced protein kinase. [refseq;acc:nm_003690]	4614.87	Low confidence	3840.85	1.20152
28	0	beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]	139	High confidence	570	4.10072
		melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798]	895.194	High confidence	1834.36	2.04912
		tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	3719.66	Low confidence	3098.94	1.2003
29	0	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]	35.5		105.5	2.97183
		potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281]	434.911	High confidence	111.278	3.90833
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08]	895.507		1834.52	2.04858
		tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	3739.84	Low confidence	3121.28	1.19818
30	0	dystrophin. [swissprot;acc:p11532]	111.739	High confidence	427.217	3.82335
		melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]	35.5	Low confidence	105.5	2.97183
	1	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	43509.4		36474.3	1.19288
		guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670]	895.633	High confidence	1834.59	2.04837
31	0	dok-like protein. [refseq;acc:nm_024872]	0.00001		35	3500000
		hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151]	895.697	High confidence	1834.63	2.04827
		vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]	43503.3	Low confidence	36469.3	1.19287
32	0	cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336]	184	High confidence	598	3.25
		melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	895.893	High confidence	1834.73	2.04793
		nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	43368.8	Low confidence	36360.3	1.19275
33	0	lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893]	39.8063	High confidence	12.6208	3.15402
		melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152]	896.972	High confidence	1835.3	2.04611
		vitelliform macular dystrophy 2-like protein 1. [refseq;acc:nm_017682]	43368.8	Low confidence	36360.3	1.19275
34	0	glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]	47	High confidence	143	3.04255
		melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [swissprot;acc:p29992]	907.546	High confidence	1836.71	2.02382
		protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8]	6352.4	Low confidence	5339.5	1.1897
35	0	adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]	1377	High confidence	459.5	2.99674
		melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]	35.5	Low confidence	105.5	2.97183
	1	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	39358.1		33111.4	1.18866
		guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	907.564	High confidence	1836.71	2.02378
36	0	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]	56		157	2.80357
		melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086]	907.741	High confidence	1836.76	2.02344
		proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100]	7593.77	Low confidence	6462.09	1.17513
37	0	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	934.348	High confidence	334.401	2.79409
		melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	35.5	Low confidence	105.5	2.97183
	1	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]	907.763	High confidence	1836.76	2.02339
		jun dimerization protein. [refseq;acc:nm_130469]	7593.77	Low confidence	6462.09	1.17513
38	0	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	35.5		105.5	2.97183
		zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623]	120.429	High confidence	320.012	2.65727

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.