MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Network Comparison Type	Rank	Value Type	Hugo	Interaction Map	red	Filtered	network_comparison	green

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Showing element 1 to 50 of 66312 in total

Filtered  : 1

description	Network Comparison Type	Rank	Value Type	Hugo	Interaction Map	red	network_comparison	green
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Divided	18	Ranked	GBE1	High confidence	185.678	1.32082	245.247
		60	Measured			4489.19	1.6231	2765.82
		64	Rooted			63.8686	1.35128	47.2654
		245	Squared			8875.01	1.31131	6768.05
		1119			Low confidence	43628.5	1.04654	41688.5
		4130	Ranked			199.383	1.01062	201.5
		4914	Measured			7853.62	1.00597	7900.54
			Rooted			71.9496	1.00944	72.6287
	Subtracted	54	Ranked		High confidence	185.678	59.569	245.247
		67	Rooted			63.8686	16.6032	47.2654
		164	Measured			4489.19	1723.37	2765.82
		1423	Squared		Low confidence	43628.5	1940	41688.5
		1962			High confidence	8875.01	2106.96	6768.05
		4141	Ranked		Low confidence	199.383	2.117	201.5
		4909	Measured			7853.62	46.92	7900.54
		4919	Rooted			71.9496	0.6791	72.6287
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	Divided	295	Squared	no value	High confidence	30807.7	1.27733	39351.7
		509	Measured			7551.8	1.14278	8630.06
		805	Rooted			74.3557	1.0645	79.1513
		885	Measured		Low confidence	8255.95	1.03993	8585.64
		1038	Ranked		High confidence	186.741	1.03148	181.041
		1092	Rooted		Low confidence	73.5001	1.0386	76.3375
		1328	Ranked			198.342	1.02218	194.038
		4562	Squared			46617.7	1.01928	45736
	Subtracted	274			High confidence	30807.7	8544	39351.7
		310	Measured			7551.8	1078.26	8630.06
		610	Rooted			74.3557	4.7956	79.1513
		780	Measured		Low confidence	8255.95	329.69	8585.64
		980	Rooted			73.5001	2.8374	76.3375
		1120	Ranked		High confidence	186.741	5.7	181.041
		1408			Low confidence	198.342	4.304	194.038
		4514	Squared			46617.7	881.7	45736
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	Divided	294		AGPAT2	High confidence	30826.5	1.2776	39383.9
		508	Measured			7556.75	1.14293	8636.87
		804	Rooted			74.3877	1.0646	79.1931
		880	Measured		Low confidence	8256.68	1.04001	8587.03
		1032	Ranked		High confidence	186.664	1.03162	180.943
		1084	Rooted		Low confidence	73.5068	1.03863	76.3467
		1322	Ranked			198.322	1.0222	194.014
		4569	Squared			46616.1	1.01914	45740.5
	Subtracted	273			High confidence	30826.5	8557.4	39383.9
		307	Measured			7556.75	1080.12	8636.87
		609	Rooted			74.3877	4.8054	79.1931
		773	Measured		Low confidence	8256.68	330.35	8587.03
		977	Rooted			73.5068	2.8399	76.3467
		1115	Ranked		High confidence	186.664	5.721	180.943
		1406			Low confidence	198.322	4.308	194.014
		4523	Squared			46616.1	875.6	45740.5
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	Divided	237	Measured	AGPAT4		8530.51	1.06457	9081.29
		311	Squared		High confidence	30566.4	1.27154	38866.5

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.