MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	network_comparison	green
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	18	GBE1	Divided	High confidence	185.678	1.32082	245.247
	54		Subtracted			59.569
	4130		Divided	Low confidence	199.383	1.01062	201.5
	4141		Subtracted			2.117
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	1038	no value	Divided	High confidence	186.741	1.03148	181.041
	1120		Subtracted			5.7
	1328		Divided	Low confidence	198.342	1.02218	194.038
	1408		Subtracted			4.304
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	1032	AGPAT2	Divided	High confidence	186.664	1.03162	180.943
	1115		Subtracted			5.721
	1322		Divided	Low confidence	198.322	1.0222	194.014
	1406		Subtracted			4.308
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	588	AGPAT4	Divided		191.507	1.03039	185.859
	664		Subtracted			5.648
	1048		Divided	High confidence	187.96	1.031	182.308
	1128		Subtracted			5.652
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	637	AGPAT3	Divided	Low confidence	192.166	1.029	186.751
	737		Subtracted			5.415
	1043		Divided	High confidence	187.834	1.03128	182.137
	1121		Subtracted			5.697
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	3423	no value	Divided	Low confidence	199.702	1.01523	196.707
	3432		Subtracted			2.995
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	3126	PLCB4	Divided	High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
	3567			Low confidence	202.517	2.889	199.628
	3585		Divided			1.01447
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	1933	HSPE1	Subtracted	High confidence	211.633	2.07	213.703
	1963		Divided			1.00978
	2659			Low confidence	200.053	1.0177	196.574
	2668		Subtracted			3.479
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	1795	ALDH1L1			203.414	3.959	199.455
	1873		Divided			1.01985
	2922			High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704]	4255	LRPPRC	Divided	Low confidence	202.306	1.00954	200.395
	4263		Subtracted			1.911
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	2076	YWHAB	Divided		198.587	1.01928	194.83
	2165		Subtracted			3.757
	2421			High confidence	220.681	0.744	221.425
	2439		Divided			1.00337
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	2864	YWHAE		Low confidence	200.418	1.01713	197.043
	2895		Subtracted			3.375
	3088		Divided	High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	2108	YWHAZ	Divided	Low confidence	198.65	1.01923	194.902
	2185		Subtracted			3.748
	2391			High confidence	220.683	0.827	221.51
	2396		Divided			1.00375
14.5 kda translational inhibitor protein (p14.5) (uk114 antigen homolog). [swissprot;acc:p52758]	1035	HRSP12	Subtracted	Low confidence	201.723	4.757	196.966
	1044		Divided			1.02415

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.