Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Value Type Gene description Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1001 to 1050 of 9634 in total
Value Type  : Measured
Network Comparison Type  : Divided
Rank
description
Interaction Map
Filtered
red
green
network_comparison
251 keratin associated protein 4-12; keratin associated protein 4.12. [refseq;acc:nm_031854] High confidence 0 1225.08 1079.38 1.13498
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [swissprot;acc:q16719] Low confidence 1 8527.55 9058.09 1.06221
tyrosine-protein kinase hck (ec 2.7.1.112) (p59-hck/p60-hck) (hemopoietic cell kinase). [swissprot;acc:p08631] High confidence 6417.18 7859.6 1.22477
zinc finger protein 74 (hznf7). [swissprot;acc:q16587] Low confidence 0 2352.49 1969.49 1.19447
252 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7] 1 8492.92 9018.94 1.06194
crk-like protein. [swissprot;acc:p46109] High confidence 6417.18 7859.6 1.22477
star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [swissprot;acc:p59095] 0 1225.08 1079.38 1.13498
zinc finger protein 285. [refseq;acc:nm_152354] Low confidence 2352.38 1969.39 1.19447
253 espin. [refseq;acc:nm_031475] High confidence 1225.07 1079.38 1.13498
fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757] Low confidence 1 8223.39 8732.25 1.06188
proto-oncogene tyrosine-protein kinase abl1 (ec 2.7.1.112) (p150) (c-abl). [swissprot;acc:p00519] High confidence 6417.18 7859.59 1.22477
zinc finger protein 117 (zinc finger protein hpf9) (fragment). [swissprot;acc:q03924] Low confidence 0 2352.42 1969.43 1.19447
254 40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47] High confidence 1318.22 1495.66 1.13461
dj842g6.2 (novel protein imilar to sel1l (sel-1 (suppressor of lin-12, c.elegans)-like)) (fragment). [sptrembl;acc:q9ugd3] Low confidence 1 8219.97 8727.87 1.06179
proto-oncogene tyrosine-protein kinase fyn (ec 2.7.1.112) (p59-fyn) (syn) (slk). [swissprot;acc:p06241] High confidence 6417.18 7859.6 1.22477
zinc finger protein 141. [swissprot;acc:q15928] Low confidence 0 2352.42 1969.43 1.19447
255 40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750] High confidence 1317.84 1495.22 1.1346
proto-oncogene tyrosine-protein kinase fgr (ec 2.7.1.112) (p55-fgr) (c-fgr). [swissprot;acc:p09769] 1 6417.18 7859.6 1.22477
sel-1 homolog precursor (suppressor of lin-12-like protein) (sel-1l). [swissprot;acc:q9ubv2] Low confidence 8219.95 8727.84 1.06179
zinc finger protein 197 (znf20). [swissprot;acc:o14709] 0 2352.58 1969.57 1.19446
256 fructose-1,6-bisphosphatase (ec 3.1.3.11) (d-fructose-1,6-bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:p09467] 1 8216.87 8723.91 1.06171
grb2-related adaptor protein 2 (gads protein) (growth factor receptor binding protein) (grblg) (grf40 adaptor protein) (grf-40) (grb-2-like protein) (grb2l) (grbx) (p38) (hematopoietic cell-associated adaptor protein grpl) (adapter protein grid) (sh3-sh2-sh3 adaptor mona). [swissprot;acc:o75791] High confidence 6417.19 7859.51 1.22476
keratin associated protein 9-4; keratin associated protein 9.4. [refseq;acc:nm_033191] 0 1224.65 1079.77 1.13418
similar to zinc finger protein 85 (zinc finger protein hpf4) (htf1). [refseq;acc:nm_033196] Low confidence 2352.58 1969.57 1.19446
257 ccaat displacement protein (cdp) (cut-like 1). [swissprot;acc:p39880] High confidence 1 6417.31 7858.12 1.22452
creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532] 0 861.401 759.896 1.13358
synaptojanin 1 (ec 3.1.3.36) (synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1). [swissprot;acc:o43426] Low confidence 1 8082.34 8579.93 1.06157
zinc finger protein mgc21738. [refseq;acc:nm_145044] 0 2352.73 1969.72 1.19445
258 40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174] High confidence 1183.16 1337.54 1.13048
aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [swissprot;acc:o95154] Low confidence 1 9249.74 9818.95 1.06154
homeobox protein cux-2 (cut-like 2) (fragment). [swissprot;acc:o14529] High confidence 6417.33 7857.93 1.22449
zinc finger protein 257 (bone marrow zinc finger 4) (bmzf-4). [swissprot;acc:q9y2q1] Low confidence 0 2352.89 1969.86 1.19445
259 60s ribosomal protein l23a. [swissprot;acc:p29316] High confidence 1295.49 1463.51 1.1297
krueppel-related zinc finger protein 1 (hkr1 protein). [swissprot;acc:p10072] Low confidence 2352.89 1969.86 1.19445
neural wiskott-aldrich syndrome protein (n-wasp). [swissprot;acc:o00401] High confidence 1 6417.81 7852.52 1.22355
oligophrenin 1. [swissprot;acc:o60890] Low confidence 6428.7 6824.22 1.06152
260 aflatoxin b1 aldehyde reductase 1 (ec 1.-.-.-) (afb1-ar 1) (aldoketoreductase 7). [swissprot;acc:o43488] 9246.23 9814.59 1.06147
signal recognition particle 9 kda protein (srp9). [swissprot;acc:p49458] High confidence 4244.95 5193.42 1.22343
voltage-dependent calcium channel gamma-5 subunit (neuronal voltage- gated calcium channel gamma-5 subunit). [swissprot;acc:q9uf02] 0 1949.36 2202 1.1296
zinc finger protein 354c; krab-zinc finger protein synten. [refseq;acc:nm_014594] Low confidence 2352.69 1969.68 1.19445
261 adrenodoxin, mitochondrial precursor (adrenal ferredoxin) (hepatoredoxin) (ferredoxin 1). [swissprot;acc:p10109] 1 8837.18 9379.17 1.06133
c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02] High confidence 0 1295.81 1463.55 1.12945
signal recognition particle 9 kda protein (srp9). [swissprot;acc:p49458] 1 4247.36 5192.61 1.22255
zinc finger protein zfd25. [swissprot;acc:q9uii5] Low confidence 0 2352.64 1969.64 1.19445
262 adenylyl cyclase-associated protein 2 (cap 2). [swissprot;acc:p40123] High confidence 764.479 676.971 1.12926
cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [refseq;acc:nm_006693] 1 24896.4 20431.7 1.21852
oligophrenin-1 like protein (gtpase regulator associated with focal adhesion kinase). [swissprot;acc:q9una1] Low confidence 6440.08 6834.37 1.06122
zinc finger protein 44 (zinc finger protein kox7) (gonadotropin inducible transcription repressor-2) (giot-2). [swissprot;acc:p15621] 0 2352.64 1969.64 1.19445
263 oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977] 1 7424.14 7877.49 1.06106
sirtuin 7; sir2-related protein type 7; sirtuin type 7; sirtuin (silent mating type information regulation 2, s.cerevisiae, homolog) 7; silent mating type information regulation 2, s.cerevisiae, homolog 7; sirtuin silent mating type information regulation 2 homolog 7 (s. cerevisiae). [refseq;acc:nm_016538] High confidence 0 1843 1633 1.1286

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/