MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	network_comparison	Gene	Interaction Map	red	Network Comparison Type	Rank	description

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	network_comparison	Interaction Map	red	Network Comparison Type	Rank	description
322.947	1.26947	Low confidence	409.972	Divided	148	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
	87.025			Subtracted	469
323.433	1.26852		410.28	Divided	150	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
	86.847			Subtracted	470
323.685	1.26808		410.457	Divided	151	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]
	86.772			Subtracted	471
327.517	1.92644	High confidence	630.942	Divided	55	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]
	303.425			Subtracted	103
330.189	1.93484		638.862	Divided	54	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]
	308.673			Subtracted	101
335	1.32937		252	Divided	133	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]
	83			Subtracted	314
336.584	1.28908		261.105	Divided	157	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]
		Low confidence			143
	75.479	High confidence		Subtracted	319
		Low confidence			497
339.154	1.19069	High confidence	403.827	Divided	207	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]
	64.673			Subtracted	331
339.779	1.06422	Low confidence	361.601	Divided	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
	21.822			Subtracted	733
346.751	1.32862	High confidence	260.986	Divided	134	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]
	85.765			Subtracted	309
351.772	1.76802		198.964	Divided	68	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]
	152.808			Subtracted	209
352.75	1.75762		620	Divided	71	ubiquitin protein ligase. [refseq;acc:nm_130466]
	267.25			Subtracted	119
354.349	1.16138	Low confidence	305.111	Divided	318	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]
	49.238			Subtracted	599
359.631	1.37479	High confidence	494.417	Divided	120	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]
	134.786			Subtracted	238
359.98	1.04852		377.445	Divided	382	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]
	17.465			Subtracted	433
362.023	1.04825		379.489	Divided	383	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]
	17.466			Subtracted	432
362.955	1.47569	Low confidence	535.61	Divided	101	60s ribosomal protein l37a. [swissprot;acc:p12751]
	172.655			Subtracted	301
363	1.19408	High confidence	304	Divided	203	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]
		Low confidence			296
	59	High confidence		Subtracted	343
		Low confidence			555
368.317	1.14829	High confidence	320.752	Divided	229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
	47.565			Subtracted	370
369.011	1.14972		424.258	Divided	227	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]
	55.247			Subtracted	349
372.961	1.29544		287.903	Divided	145	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]
	85.058			Subtracted	312
375.343	1.21433	Low confidence	455.789	Divided	179	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]
	80.446			Subtracted	481
377.574	1.29466	High confidence	291.639	Divided	146	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]
	85.935			Subtracted	308

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.