Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Filtered Value Type green network_comparison red Interaction Map Gene Rank Network Comparison Type
Results: HTML CSV LaTeX Showing element 1 to 50 of 77072 in total
description
Filtered
Value Type
green
network_comparison
red
Interaction Map
Rank
Network Comparison Type
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 0 Measured 851.77 1.31954 645.504 Low confidence 131 Divided
206.266 273 Subtracted
934.348 2.79409 334.401 High confidence 37 Divided
599.947 45 Subtracted
Ranked 13590.3 1.02915 13205.3 Low confidence 629 Divided
385 600 Subtracted
13895.8 1.09822 15260.6 High confidence 242 Divided
1364.8 172 Subtracted
Squared 1034.13 10.2338 101.05 37 Divided
933.08 131 Subtracted
1268.51 1.63527 775.72 Low confidence 146 Divided
492.79 319 Subtracted
Rooted 17.0804 0.7824 16.298 634
1.04801 537 Divided
18.0183 1.5213 11.844 High confidence 53
6.1743 69 Subtracted
1 Measured 2765.82 1.6231 4489.19 60 Divided
1723.37 164 Subtracted
7900.54 1.00597 7853.62 Low confidence 4914 Divided
46.92 4909 Subtracted
Ranked 201.5 1.01062 199.383 4130 Divided
2.117 4141 Subtracted
245.247 1.32082 185.678 High confidence 18 Divided
59.569 54 Subtracted
Squared 6768.05 1.31131 8875.01 245 Divided
2106.96 1962 Subtracted
41688.5 1.04654 43628.5 Low confidence 1119 Divided
1940 1423 Subtracted
Rooted 47.2654 1.35128 63.8686 High confidence 64 Divided
16.6032 67 Subtracted
72.6287 0.6791 71.9496 Low confidence 4919
1.00944 4914 Divided
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943] Measured 8585.64 1.03993 8255.95 885
329.69 780 Subtracted
8630.06 1.14278 7551.8 High confidence 509 Divided
1078.26 310 Subtracted
Ranked 181.041 1.03148 186.741 1038 Divided
5.7 1120 Subtracted
194.038 1.02218 198.342 Low confidence 1328 Divided
4.304 1408 Subtracted
Squared 39351.7 1.27733 30807.7 High confidence 295 Divided
8544 274 Subtracted
45736 1.01928 46617.7 Low confidence 4562 Divided
881.7 4514 Subtracted
Rooted 76.3375 1.0386 73.5001 1092 Divided
2.8374 980 Subtracted
79.1513 1.0645 74.3557 High confidence 805 Divided
4.7956 610 Subtracted
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120] Measured 8587.03 1.04001 8256.68 Low confidence 880 Divided
330.35 773 Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/