MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Interaction Map	network_comparison	Filtered	Gene	Value Type	green	Network Comparison Type	red

Results: HTML CSV LaTeX

Showing element 1 to 16 of 16 in total

Rank  : 37
Network Comparison Type  : Divided

description	Interaction Map	network_comparison	Filtered	Value Type	green	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	High confidence	2.79409	0	Measured	934.348	334.401
		10.2338		Squared	1034.13	101.05
chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0]	Low confidence	1.14874	1	Ranked	217.843	250.244
dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]	High confidence	1.49458	0		2582	3859
guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]		1.65293	1	Rooted	24.3691	40.2805
		2.02339		Measured	907.763	1836.76
jun dimerization protein. [refseq;acc:nm_130469]	Low confidence	1.17513			7593.77	6462.09
melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]		9.62112	0	Squared	0.355148	3.41692
melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]		1.69589		Rooted	5.80678	9.84765
melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]		2.97183		Measured	35.5	105.5
melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]		1.33073	1	Squared	61881.5	82347.8
myotubularin related protein 8. [refseq;acc:nm_017677]		1.36786	0	Ranked	8993.6	12302
pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23]	High confidence	1.80879	1	Squared	192141	106226
protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256]		1.27273		Ranked	253	322
small nuclear ribonucleoprotein associated proteins b and b' (snrnp-b) (sm protein b/b') (sm-b/sm-b') (smb/smb'). [swissprot;acc:p14678]		1.94348	0	Rooted	9.39626	4.83477
testis-specific protein tex28. [swissprot;acc:o15482]	Low confidence	1.14428	1		59.166	51.7058

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.