Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Value Type green Filtered Interaction Map network_comparison red Gene Rank Network Comparison Type
Results: HTML CSV LaTeX Showing element 451 to 500 of 77072 in total
Filtered  : 1
description
Value Type
green
Interaction Map
network_comparison
red
Rank
Network Comparison Type
26s protease regulatory subunit 6a (tat-binding protein 1) (tbp-1) (proteasome subunit p50). [swissprot;acc:p17980] Measured 8372.5 Low confidence 1.03218 8111.49 2003 Divided
261.01 1841 Subtracted
Ranked 196.948 1.01795 200.484 2595 Divided
3.536 2596 Subtracted
217.285 High confidence 0.645 216.64 2466
1.00298 2474 Divided
Squared 30410 1.11409 27295.8 1496
3114.2 1181 Subtracted
44725.2 Low confidence 1.0303 46080.5 3788 Divided
1355.3 3664 Subtracted
Rooted 64.4831 High confidence 1.02878 62.679 1916 Divided
1.8041 1949 Subtracted
75.0673 Low confidence 1.03422 72.5833 2293 Divided
2.484 2219 Subtracted
26s protease regulatory subunit 6b (mip224) (mb67 interacting protein) (tat-binding protein-7) (tbp-7). [swissprot;acc:p43686] Measured 6242.94 High confidence 1.07226 5822.25 1567 Divided
420.69 1628 Subtracted
8556.58 Low confidence 1.03623 8257.44 1203 Divided
299.14 1060 Subtracted
Ranked 195.763 1.01951 199.582 1991 Divided
3.819 2044 Subtracted
218.426 High confidence 1.00466 217.413 2327 Divided
1.013 2323 Subtracted
Squared 29299.3 1.115 26277.3 1489 Divided
3022 1222 Subtracted
46205.5 Low confidence 1.01772 47024.3 4609 Divided
818.8 4581 Subtracted
Rooted 63.9055 High confidence 1.02686 62.2342 2044 Divided
1.6713 2043 Subtracted
75.8817 Low confidence 1.03591 73.251 1667 Divided
2.6307 1542 Subtracted
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998] Measured 6207.5 High confidence 1.07322 5783.97 1539 Divided
423.53 1622 Subtracted
8703.92 Low confidence 1.03794 8385.76 1024 Divided
318.16 877 Subtracted
Ranked 194.732 1.01866 198.366 2321 Divided
3.634 2407 Subtracted
219.014 High confidence 0.822 218.192 2394
1.00377 2395 Divided
Squared 29163.8 1.11557 26142.6 1481
3021.2 1224 Subtracted
47560.6 Low confidence 1.00838 47959.2 4841 Divided
398.6 4819 Subtracted
Rooted 63.6738 High confidence 1.02776 61.9542 1979 Divided
1.7196 2006 Subtracted
76.5062 Low confidence 1.03544 73.8873 1844 Divided
2.6189 1578 Subtracted
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210] Measured 8314.51 1.02789 8088.94 3044 Divided
225.57 2944 Subtracted
9234.09 High confidence 1.00914 9150.44 2651 Divided
83.65 2602 Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/