Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene Network Comparison Type Hugo description Value Type Interaction Map Filtered network_comparison red green
Results: HTML CSV LaTeX Showing element 1 to 50 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
Network Comparison Type
Hugo
description
network_comparison
red
green
1 Divided UBAC1 putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172] 2.4 10 24
Subtracted HLX homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774] 107 215 322
2 Divided no value mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476] 1.86667 15 28
Subtracted HBS1L hbs1-like. [refseq;acc:nm_006620] 107 215 322
3 Divided PSCD1 cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438] 1.86667 15 28
Subtracted RINT1 rad50-interacting protein 1. [refseq;acc:nm_021930] 105 337 232
4 Divided PSCD2 cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418] 1.86667 15 28
Subtracted RHOBTB2 rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6] 105 337 232
5 Divided PSCD4 cytohesin 4. [swissprot;acc:q9uia0] 1.86667 15 28
Subtracted XAB1 xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 97 212 309
6 Divided PSCD3 cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739] 1.86667 15 28
Subtracted ATPBD1C protein x 0004. [refseq;acc:nm_016301] 97 212 309
7 Divided HLX homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774] 1.49767 215 322
Subtracted UFC1 protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 76.2 288.754 212.554
8 Divided HBS1L hbs1-like. [refseq;acc:nm_006620] 1.49767 215 322
Subtracted JPH3 junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2] 74 288 362
9 Divided XAB1 xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] 1.45755 212 309
Subtracted JPH2 junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39] 74 288 362
10 Divided ATPBD1C protein x 0004. [refseq;acc:nm_016301] 1.45755 212 309
Subtracted SMPD2 sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906] 74 288 362
11 Divided RINT1 rad50-interacting protein 1. [refseq;acc:nm_021930] 1.45259 337 232
Subtracted TMEM33 db83 protein. [swissprot;acc:p57088] 74 288 362
12 Divided RHOBTB2 rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6] 1.45259 337 232
Subtracted no value guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-7 subunit. [swissprot;acc:o60262] 69.377 266.856 336.233
13 Divided UFC1 protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 1.3585 288.754 212.554
Subtracted GNG12 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6] 69.377 266.856 336.233
14 Divided ATG4A cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] 1.32952 56.6768 75.3531
Subtracted GNG4 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150] 69.328 266.863 336.191
15 Divided MAP1LC3B microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] 1.32914 56.7244 75.3948
Subtracted GNG3 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798] 69.327 266.863 336.19
16 Divided MAP1LC3A microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] 1.32913 56.7252 75.3954
Subtracted GNG8 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08] 69.32 266.864 336.184
17 Divided ATG4B cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] 1.32866 56.7841 75.447
Subtracted GNG5 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670] 69.318 266.864 336.182
18 Divided GBE1 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 1.32082 185.678 245.247
Subtracted GNG10 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151] 69.316 266.865 336.181
19 Divided PYGB glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216] 1.32082 185.678 245.247
Subtracted no value guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8] 69.313 266.865 336.178
20 Divided PYGL glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737] 1.32082 185.678 245.247
Subtracted GNG11 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152] 69.291 266.868 336.159
21 Divided MYO15A myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7] 1.32082 185.678 245.247
Subtracted TMEM132A gbp protein isoform a. [refseq;acc:nm_017870] 69.094 325.586 256.492
22 Divided PYGM glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217] 1.32082 185.678 245.247
Subtracted PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14a; 17-kda pkc-potentiated inhibitory protein of pp1. [refseq;acc:nm_033256] 69 322 253
23 Divided MRPS17 28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5] 1.31818 58 44
Subtracted MFAP4 microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083] 69 322 253
24 Divided PANK1 pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04] 1.31818 58 44
Subtracted PPP1R14D protein phosphatase 1, regulatory subunit 14d; pkc-dependent pp1 inhibitory protein. [refseq;acc:nm_017726] 69 322 253
25 Divided PANK2 pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23] 1.31818 58 44
Subtracted FCN2 ficolin 2 precursor (collagen/fibrinogen domain-containing protein 2) (ficolin-b) (ficolin b) (serum lectin p35) (ebp-37) (hucolin) (l- ficolin). [swissprot;acc:q15485] 69 322 253

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/