MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	Value Type	Network Comparison Type	green	description	network_comparison	Interaction Map	red	Filtered

Results: HTML CSV LaTeX

Showing element 1 to 50 of 29840 in total

Interaction Map  : High confidence

Rank	Value Type	Network Comparison Type	green	description	network_comparison	red	Filtered
1	Measured	Divided	0.00001	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	36400000	364	0
			2394.5	rad50-interacting protein 1. [refseq;acc:nm_021930]	5.31521	450.5	1
		Subtracted	6410	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	6325	85	0
			33356.5	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	8126	41482.5	1
	Ranked	Divided	24	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	2.4	10
			15915	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	3.70633	4294	0
		Subtracted	322	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	107	215	1
			21883	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	12977	8906	0
	Squared	Divided	7.16592	cab2. [refseq;acc:nm_033419]	716592	0.00001
			1357.07	rad50-interacting protein 1. [refseq;acc:nm_021930]	28.2513	48.0356	1
		Subtracted	160184	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	72283	232467	0
			322755	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	145743	468498	1
	Rooted	Divided	0.00001	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	1907880	19.0788	0
			48.9336	rad50-interacting protein 1. [refseq;acc:nm_021930]	2.30547	21.225	1
		Subtracted			27.7086
			60.0707	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	50.8706	9.20014	0
2	Measured	Divided	174	cab2. [refseq;acc:nm_033419]	17400000	0.00001
			2394.5	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	5.31521	450.5	1
		Subtracted	6410	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	6325	85	0
			33356.5	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	8126	41482.5	1
	Ranked	Divided	28	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	1.86667	15
			14977	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	2.55362	5865	0
		Subtracted	322	hbs1-like. [refseq;acc:nm_006620]	107	215	1
			15915	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	11621	4294	0
	Squared	Divided	0.00001	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	561325	5.61325
			1357.07	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	28.2513	48.0356	1
		Subtracted	263351	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	143938	407289
			345123	histone h4. [swissprot;acc:p02304]	71500	273623	0
	Rooted	Divided	0.00001	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	1240970	12.4097
			48.9336	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	2.30547	21.225	1
		Subtracted			27.7086
			60.0707	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	50.8706	9.20014	0
3	Measured	Divided	109	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]	10900000	0.00001
			698.5	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	3.71868	2597.5	1
		Subtracted	19621.3	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	4196.8	23818.1	0
			33356.5	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	8126	41482.5	1
	Ranked	Divided	28	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	1.86667	15
			11083.9	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]	2.47638	4475.84	0
		Subtracted	232	rad50-interacting protein 1. [refseq;acc:nm_021930]	105	337	1
			10950	cab2. [refseq;acc:nm_033419]	10916	21866	0
	Squared	Divided	0.00001	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	561325	5.61325
			115.48	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	13.8285	1596.92	1
		Subtracted	170628	apoptosis inhibitor fksg2. [swissprot;acc:q9hau6]	35348	135280	0
			263351	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	143938	407289	1
	Rooted	Divided	0.00001	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	1240970	12.4097	0
			26.4292	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	1.92839	50.9657	1
		Subtracted	6.85565	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	30.0631	36.9188	0
			26.4292	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	24.5365	50.9657	1
4	Measured	Divided	89	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	8900000	0.00001	0
			698.5	hbs1-like. [refseq;acc:nm_006620]	3.71868	2597.5	1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.