MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Filtered	Rank	Interaction Map	Value Type	green	red	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	Rank	Interaction Map	Value Type	green	red	network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	37	High confidence	Measured	934.348	334.401	2.79409
				Squared	1034.13	101.05	10.2338
		53		Rooted	18.0183	11.844	1.5213
		131	Low confidence	Measured	851.77	645.504	1.31954
		146		Squared	1268.51	775.72	1.63527
		242	High confidence	Ranked	13895.8	15260.6	1.09822
		537	Low confidence	Rooted	17.0804	16.298	1.04801
		629		Ranked	13590.3	13205.3	1.02915
	1	18	High confidence		245.247	185.678	1.32082
		60		Measured	2765.82	4489.19	1.6231
		64		Rooted	47.2654	63.8686	1.35128
		245		Squared	6768.05	8875.01	1.31131
		1119	Low confidence		41688.5	43628.5	1.04654
		4130		Ranked	201.5	199.383	1.01062
		4914		Measured	7900.54	7853.62	1.00597
				Rooted	72.6287	71.9496	1.00944
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]		295	High confidence	Squared	39351.7	30807.7	1.27733
		509		Measured	8630.06	7551.8	1.14278
		805		Rooted	79.1513	74.3557	1.0645
		885	Low confidence	Measured	8585.64	8255.95	1.03993
		1038	High confidence	Ranked	181.041	186.741	1.03148
		1092	Low confidence	Rooted	76.3375	73.5001	1.0386
		1328		Ranked	194.038	198.342	1.02218
		4562		Squared	45736	46617.7	1.01928
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]		294	High confidence		39383.9	30826.5	1.2776
		508		Measured	8636.87	7556.75	1.14293
		804		Rooted	79.1931	74.3877	1.0646
		880	Low confidence	Measured	8587.03	8256.68	1.04001
		1032	High confidence	Ranked	180.943	186.664	1.03162
		1084	Low confidence	Rooted	76.3467	73.5068	1.03863
		1322		Ranked	194.014	198.322	1.0222
		4569		Squared	45740.5	46616.1	1.01914
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]		237		Measured	9081.29	8530.51	1.06457
		311	High confidence	Squared	38866.5	30566.4	1.27154
		378	Low confidence	Rooted	79.5804	75.8843	1.04871
		514	High confidence	Measured	8532.02	7477	1.1411
		588	Low confidence	Ranked	185.859	191.507	1.03039
		822	High confidence	Rooted	78.5795	73.8577	1.06393
		1048		Ranked	182.308	187.96	1.031
		4138	Low confidence	Squared	47372.8	46138.2	1.02676
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]		252		Measured	9018.94	8492.92	1.06194
		308	High confidence	Squared	38919.9	30596.2	1.27205
		427	Low confidence	Rooted	79.1997	75.6219	1.04731
		513	High confidence	Measured	8543.66	7485.08	1.14143
		637	Low confidence	Ranked	186.751	192.166	1.029
		811	High confidence	Rooted	78.6514	73.9102	1.06415
		1043		Ranked	182.137	187.834	1.03128
		4418	Low confidence	Squared	47088.3	46049.4	1.02256
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]		2035		Measured	8323.04	8065.05	1.03199
		2766		Rooted	74.9741	72.5914	1.03282

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.