MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Filtered	green	Interaction Map	Gene	Value Type	Rank	red	network_comparison	Network Comparison Type

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Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	green	Interaction Map	Value Type	Rank	red	network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	17.0804	Low confidence	Rooted	537	16.298	1.04801
		18.0183	High confidence		53	11.844	1.5213
		851.77	Low confidence	Measured	131	645.504	1.31954
		934.348	High confidence		37	334.401	2.79409
		1034.13		Squared		101.05	10.2338
		1268.51	Low confidence		146	775.72	1.63527
		13590.3		Ranked	629	13205.3	1.02915
		13895.8	High confidence		242	15260.6	1.09822
	1	47.2654		Rooted	64	63.8686	1.35128
		72.6287	Low confidence		4914	71.9496	1.00944
		201.5		Ranked	4130	199.383	1.01062
		245.247	High confidence		18	185.678	1.32082
		2765.82		Measured	60	4489.19	1.6231
		6768.05		Squared	245	8875.01	1.31131
		7900.54	Low confidence	Measured	4914	7853.62	1.00597
		41688.5		Squared	1119	43628.5	1.04654
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]		76.3375		Rooted	1092	73.5001	1.0386
		79.1513	High confidence		805	74.3557	1.0645
		181.041		Ranked	1038	186.741	1.03148
		194.038	Low confidence		1328	198.342	1.02218
		8585.64		Measured	885	8255.95	1.03993
		8630.06	High confidence		509	7551.8	1.14278
		39351.7		Squared	295	30807.7	1.27733
		45736	Low confidence		4562	46617.7	1.01928
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]		76.3467		Rooted	1084	73.5068	1.03863
		79.1931	High confidence		804	74.3877	1.0646
		180.943		Ranked	1032	186.664	1.03162
		194.014	Low confidence		1322	198.322	1.0222
		8587.03		Measured	880	8256.68	1.04001
		8636.87	High confidence		508	7556.75	1.14293
		39383.9		Squared	294	30826.5	1.2776
		45740.5	Low confidence		4569	46616.1	1.01914
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]		78.5795	High confidence	Rooted	822	73.8577	1.06393
		79.5804	Low confidence		378	75.8843	1.04871
		182.308	High confidence	Ranked	1048	187.96	1.031
		185.859	Low confidence		588	191.507	1.03039
		8532.02	High confidence	Measured	514	7477	1.1411
		9081.29	Low confidence		237	8530.51	1.06457
		38866.5	High confidence	Squared	311	30566.4	1.27154
		47372.8	Low confidence		4138	46138.2	1.02676
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]		78.6514	High confidence	Rooted	811	73.9102	1.06415
		79.1997	Low confidence		427	75.6219	1.04731
		182.137	High confidence	Ranked	1043	187.834	1.03128
		186.751	Low confidence		637	192.166	1.029
		8543.66	High confidence	Measured	513	7485.08	1.14143
		9018.94	Low confidence		252	8492.92	1.06194
		38919.9	High confidence	Squared	308	30596.2	1.27205
		47088.3	Low confidence		4418	46049.4	1.02256
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]		74.9741		Rooted	2766	72.5914	1.03282
		196.707		Ranked	3423	199.702	1.01523

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.