Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Value Type Gene Network Comparison Type green network_comparison red Interaction Map Rank description
Results: HTML CSV LaTeX Showing element 501 to 550 of 77072 in total
Filtered  : 0
Value Type  : Measured
Network Comparison Type  : Divided
green
network_comparison
red
Interaction Map
Rank
description
958.726 1.05539 1011.83 Low confidence 524 keratin associated protein 1.5. [refseq;acc:nm_031957]
525 keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]
958.728 522 keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4]
526 keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]
958.732 1.05538 527 keratin associated protein 4-10; keratin associated protein 4.10. [refseq;acc:nm_033060]
958.745 1.05537 531 keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059]
532 keratin associated protein 4.9 (fragment). [sptrembl;acc:q9byq8]
958.748 1.05538 1011.84 528 keratin associated protein 4-12; keratin associated protein 4.12. [refseq;acc:nm_031854]
958.749 529 star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [swissprot;acc:p59095]
958.753 1.05537 530 similar to peptidylprolyl isomerase a (cyclophilin a); cyclophilin-lc; cyclophilin homolog overexpressed in liver cancer; chromosome 1 amplified sequence 2. [refseq;acc:nm_178230]
959.463 1.05484 1012.08 536 keratin associated protein 9-4; keratin associated protein 9.4. [refseq;acc:nm_033191]
961.098 1.00278 958.429 High confidence 484 scribble. [refseq;acc:nm_015356]
965.202 1.2878 749.494 Low confidence 144 associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]
969.022 1.00304 966.085 810 elongation factor 1-alpha 1 (ef-1-alpha-1) (elongation factor 1 a-1) (eef1a-1) (elongation factor tu) (ef-tu). [swissprot;acc:p04720]
971.37 1.00552 976.734 794 dystrophin. [swissprot;acc:p11532]
975 1.5625 624 90 rna transcribed from l1 repetitive element (shr4) (fragment). [sptrembl;acc:q9y443]
91 putative p150. [sptrembl;acc:o00370]
92 lamin-like protein in hindiii repetitive element derived dna, 3' end (fragment). [sptrembl;acc:q14755]
93 line-1 reverse transcriptase (fragment). [sptrembl;acc:o00172]
975.647 1.12024 870.93 High confidence 277 disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]
Low confidence 367
977 1.47595 1442 High confidence 101 putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7]
102 phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]
988.882 1.06044 1048.65 369 dna directed rna polymerase ii polypeptide j-related gene isoform 1; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_145325]
989.438 1.06041 1049.21 370 dna directed rna polymerase ii polypeptide j-related gene isoform 3; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_032959]
991.072 1.11025 1100.34 Low confidence 391 proto-oncogene tyrosine-protein kinase src (ec 2.7.1.112) (p60-src) (c-src). [swissprot;acc:p12931]
992.083 1.73441 572 High confidence 72 60s ribosomal protein l21. [swissprot;acc:p46778]
994.275 1.02465 1018.78 Low confidence 662 spectrin alpha chain, brain (spectrin, non-erythroid alpha chain) (alpha-ii spectrin) (fodrin alpha chain). [swissprot;acc:q13813]
1005.42 1.09699 916.527 411 mitochondrial ribosomal protein l38. [refseq;acc:nm_032478]
1006.57 1.00558 1012.19 792 dj850e9.1 (novel c2h2 type zinc finger protein similar to drosophila scratch (scrt), slug and xenopus snail) (fragment). [sptrembl;acc:q9nq03]
1010.2 1.06023 952.812 498 solute carrier family 4, sodium bicarbonate cotransporter, member 8. [refseq;acc:nm_004858]
1011.49 1.01291 1024.55 745 tera protein. [refseq;acc:nm_021238]
1011.67 1.37602 1392.08 112 transcription factor e2f2 (e2f-2). [swissprot;acc:q14209]
1015.49 1.00479 1020.35 798 scratch; scratch 1. [refseq;acc:nm_031309]
1020.78 1.16449 876.587 315 dna directed rna polymerase ii polypeptide j-related gene isoform 3; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_032959]
1020.84 1.16456 314 dna directed rna polymerase ii polypeptide j-related gene isoform 1; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_145325]
1023.76 1.22025 1249.24 High confidence 189 pyrroline-5-carboxylate reductase (ec 1.5.1.2) (p5cr) (p5c reductase). [swissprot;acc:p32322]
1026.18 1.19915 1230.54 199 glutamine synthetase (ec 6.3.1.2) (glutamate--ammonia ligase). [swissprot;acc:p15104]
1035.81 1.03681 1073.94 Low confidence 599 60s ribosomal protein l15. [swissprot;acc:p39030]
1036.1 1.10804 1148.04 393 dynamin-like 120 kda protein, mitochondrial precursor (optic atrophy 1 gene protein). [swissprot;acc:o60313]
1049.11 1.36592 768.061 114 calponin h2, smooth muscle (neutral calponin). [swissprot;acc:q99439]
1060 1.05047 1113.5 558 histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
559 histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]
560 histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]
561 h2a histone family, member j isoform 1. [refseq;acc:nm_018267]
1061.23 1.04494 1108.92 576 solute carrier family 12 (potassium/chloride transporters), member 9; cation-chloride cotransporter-interacting protein. [refseq;acc:nm_020246]
1063.6 1.2107 1287.7 183 regulator of chromosome condensation (cell cycle regulatory protein). [swissprot;acc:p18754]
1066.67 1.03569 1104.74 602 alpha 2 globin. [refseq;acc:nm_000517]
1067.65 1.03559 1105.65 604 hemoglobin gamma-a and gamma-g chains. [swissprot;acc:p02096]
1068 1.75947 607 High confidence 70 importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/