Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Hugo Gene description Network Comparison Type Value Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 6141 to 6190 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
Hugo
description
Network Comparison Type
red
green
network_comparison
3071 STK38 serine/threonine kinase 38; serine threonine protein kinase. [refseq;acc:nm_007271] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3072 PAK1IP1 pak1 interacting protein 1; pak1-interacting protein; pak/plc-interacting protein 1. [refseq;acc:nm_017906] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3073 RWDD1 rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3074 NT5DC3 tu12b1-ty protein. [refseq;acc:nm_016575] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3075 USP5 ubiquitin carboxyl-terminal hydrolase 5 (ec 3.1.2.15) (ubiquitin thiolesterase 5) (ubiquitin-specific processing protease 5) (deubiquitinating enzyme 5) (isopeptidase t). [swissprot;acc:p45974] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3076 no value placental protein 11 precursor (ec 3.4.21.-) (pp11). [swissprot;acc:p21128] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3077 H2AFJ h2a histone family, member j isoform 1. [refseq;acc:nm_018267] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3078 CREBL2 camp responsive element binding protein-like 2. [refseq;acc:nm_001310] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3079 CYP27B1 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3080 no value nucleosome assembly protein 1-like 4 (nucleosome assembly protein 2) (nap2). [swissprot;acc:q99733] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3081 PTPMT1 nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3082 CRYAB alpha crystallin b chain (alpha(b)-crystallin) (rosenthal fiber component). [swissprot;acc:p02511] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3083 GLRB glycine receptor beta chain precursor (glycine receptor 58 kda subunit). [swissprot;acc:p48167] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3084 MAP2K1IP1 mitogen-activated protein kinase kinase 1 interacting protein 1 (mek binding partner 1) (mp1) (pro2783). [swissprot;acc:q9uha4] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3085 UGT2B10 udp-glucuronosyltransferase 2b10 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:p36537] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3086 no value udp-glucuronosyltransferase 2b15 precursor, microsomal (ec 2.4.1.17) (udpgt) (udpgth-3) (hlug4). [swissprot;acc:p54855] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3087 ALDOC fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3088 YWHAE 14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3089 PRKAR1A camp-dependent protein kinase type i-alpha regulatory chain (tissue- specific extinguisher-1) (tse1). [swissprot;acc:p10644] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3090 EZH1 enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3091 MLX transcription factor-like protein 4 (max-like bhlhzip protein) (bigmax protein) (mlx). [swissprot;acc:q9uh92] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3092 DRG2 developmentally regulated gtp-binding protein 2 (drg 2). [swissprot;acc:p55039] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3093 no value ptd016 protein. [refseq;acc:nm_016125] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3094 UBE2S ubiquitin-conjugating enzyme e2-24 kda (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2-epf5). [swissprot;acc:q16763] Divided 0.00001 0.00001 1
Subtracted 0 0 0
3095 C10orf137 erythroid differentiation-related factor 1. [refseq;acc:nm_015608] Divided 0.00001 0.00001 1
Subtracted 0 0 0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/