MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	description	Interaction Map	network_comparison	Gene	red	Rank	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Filtered  : 0
Value Type  : Measured
Network Comparison Type  : Divided

green	description	Interaction Map	network_comparison	red	Rank
0.00001	brca1 associated protein. [refseq;acc:nm_006768]	High confidence	1	0.00001	502
	carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615]	Low confidence	3700000	37	22
	carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267]				23
	cobw-like protein. [refseq;acc:nm_018491]		1	0.00001	839
	dok-like protein. [refseq;acc:nm_024872]	High confidence	3500000	35	31
	ero1-like. [refseq;acc:nm_014584]		8200000	82	20
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Low confidence	1	0.00001	838
	gamma-glutamyltransferase. [sptrembl;acc:q14390]				841
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]				842
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]				837
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]				843
	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	High confidence			501
	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]				495
	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]				494
	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]				497
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]				499
		Low confidence	1300000	13	6
	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	High confidence	36400000	364	1
		Low confidence
	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	High confidence	1	0.00001	496
	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]	Low confidence	28600000	286	44
	neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]				45
	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	High confidence	15400000	154	95
	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]		1800000	18	65
	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]		1	0.00001	500
	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]		6000000	60	22
	tbc1 domain family, member 8 (with gram domain); vascular rab-gap/tbc-containing. [refseq;acc:nm_007063]	Low confidence	231962	2.31962	7
	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	High confidence	15400000	154	96
	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]		1	0.00001	498
		Low confidence			840
5.56738	serpin b12. [swissprot;acc:q96p63]	High confidence	35.8425	199.549	11
		Low confidence			10
5.71669	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]	High confidence	34.8539	199.249	12
		Low confidence			11
6.50325	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	High confidence	20.0687	130.512	14
10.6048	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]	Low confidence	36.1876	383.762	9
11.5	protocadherin 16 precursor (cadherin 19) (cadherin fibroblast 1). [swissprot;acc:q96jq0]	High confidence	1.21739	14	190
		Low confidence			176
14.3333	4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	High confidence	1.3721	19.6667	121
15	protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992]		15	1	16
17.5166	jumonji protein. [swissprot;acc:q92833]	Low confidence	1751660	0.00001	5
17.6611	syntaxin 10 (syn10). [swissprot;acc:o60499]	High confidence	6.73106	118.878	21
18	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]		1800000	0.00001	64
19	adp-ribosylation factor-like protein 7 (adp-ribosylation factor-like protein lak). [swissprot;acc:p56559]		1.21053	23	195
		Low confidence			184
	camp-regulated phosphoprotein 19 (arpp-19) [contains: camp-regulated phosphoprotein 16 (arpp-16)]. [swissprot;acc:p56211]		5.21053	99	18
21	transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884]	High confidence	2.09524	44	50
23.6984	dna helicase homolog (fragment). [sptrembl;acc:q9y645]	Low confidence	2.03615	48.2534	64
26.1599	25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	High confidence	11.6763	305.45	19
	60s ribosomal protein l37a. [swissprot;acc:p12751]				18

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.