Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type description Interaction Map Rank Network Comparison Type Gene red green network_comparison Filtered
Results: HTML CSV LaTeX Showing element 2675 to 2724 of 3228 in total 
Value Type	Measured
Interaction Map	High confidence
Network Comparison Type	Divided
Filtered	1

description	Rank	red	green	network_comparison	
splicing factor 3 subunit 1 (spliceosome associated protein 114) (sap 114) (sf3a120). [source:swissprot;acc:q15459]	649	5248.07	5901.72	1.12455	
splicing factor 3a subunit 2 (spliceosome associated protein 62) (sap 62) (sf3a66). [source:swissprot;acc:q15428]	296	4911.81	5909.18	1.20306	
splicing factor 3a subunit 3 (spliceosome associated protein 61) (sap 61) (sf3a60). [source:swissprot;acc:q12874]	648	5248.07	5901.72	1.12455	
splicing factor 3b subunit 1 (spliceosome associated protein 155) (sap 155) (sf3b155) (pre-mrna splicing factor sf3b 155 kda subunit). [source:swissprot;acc:o75533]	191	4638.1	5923.4	1.27712	
splicing factor 3b subunit 2 (spliceosome associated protein 145) (sap 145) (sf3b150) (pre-mrna splicing factor sf3b 145 kda subunit). [source:swissprot;acc:q13435]	348	4991.02	5885.09	1.17914	
splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [source:swissprot;acc:q15393]	207	4771.21	5961.43	1.24946	
splicing factor 3b subunit 4 (spliceosome associated protein 49) (sap 49) (sf3b50) (pre-mrna splicing factor sf3b 49 kda subunit). [source:swissprot;acc:q15427]	1224	4331.35	4700.91	1.08532	
splicing factor 4 isoform b; rna-binding protein. [source:refseq;acc:nm_021164]	395	4532.73	5269.33	1.16251	
splicing factor arginine/serine-rich 11 (arginine-rich 54 kda nuclear protein) (p54). [source:swissprot;acc:q05519]	1976	5939.85	6294.91	1.05978	
splicing factor u2af 35 kda subunit (u2 auxiliary factor 35 kda subunit) (u2 snrnp auxiliary factor small subunit). [source:swissprot;acc:q01081]	1959	5448.35	5777.35	1.06039	
splicing factor u2af 65 kda subunit (u2 auxiliary factor 65 kda subunit) (u2 snrnp auxiliary factor large subunit) (hu2af(65)). [source:swissprot;acc:p26368]	1961	5448.35	5777.35	1.06039	
splicing factor, arginine/serine-rich 1 (pre-mrna splicing factor sf2, p33 subunit) (alternative splicing factor asf-1). [source:swissprot;acc:q07955]	2549	4725.79	4824.4	1.02087	
splicing factor, arginine/serine-rich 3 (pre-mrna splicing factor srp20) (x16 protein). [source:swissprot;acc:p23152]	889	5903.18	6506.32	1.10217	
splicing factor, arginine/serine-rich 8 (suppressor of white apricot protein homolog). [source:swissprot;acc:q12872]	2267	9146.11	8743.98	1.04599	
splicing factor, proline-and glutamine-rich (polypyrimidine tract- binding protein-associated splicing factor) (ptb-associated splicing factor) (psf) (dna-binding p52/p100 complex, 100 kda subunit). [source:swissprot;acc:p23246]	2070	10178.5	9638.08	1.05607	
sporulation-induced transcript 4-associated protein. [source:refseq;acc:nm_018312]	1512	7234.61	7771.58	1.07422	
sprouty homolog 1 (spry-1) (fragment). [source:swissprot;acc:o43609]	676	5549.2	6215.42	1.12006	
sprouty homolog 2 (spry-2). [source:swissprot;acc:o43597]	677	5549.2	6215.42	1.12006	
sprouty homolog 3 (spry-3). [source:swissprot;acc:o43610]	675	5549.2	6215.42	1.12006	
sprouty homolog 4 (spry-4). [source:swissprot;acc:q9c004]	674	5549.2	6215.42	1.12006	
spry domain-containing socs box protein ssb-1. [source:refseq;acc:nm_025106]	2814	0.00001	0.00001	1	
spry domain-containing socs box protein ssb-4. [source:refseq;acc:nm_080862]	2806	0.00001	0.00001	1	
squalene monooxygenase (ec 1.14.99.7) (squalene epoxidase) (se). [source:swissprot;acc:q14534]	2166	6952.66	7315.06	1.05212	
squamous cell carcinoma antigen 1 (scca-1) (protein t4-a). [source:swissprot;acc:p29508]	1694	5767.69	6165.87	1.06904	
squamous cell carcinoma antigen recognized by t cells 1; u4/u6.u5 tri-snrnp-associated 110 kda protein; ige autoantigen; sart1(259) protein; sart1(800) protein. [source:refseq;acc:nm_005146]	310	4909.79	5878.79	1.19736	
sqv-7-like protein (fragment). [source:sptrembl;acc:o95454]	2222	5309.65	5066.82	1.04793	
sr rich protein. [source:refseq;acc:nm_032870]	2257	6245.32	6534.23	1.04626	
ss18-like protein 1 (syt homolog-1). [source:swissprot;acc:o75177]	2766	0.00001	0.00001	1	
ssxt protein (synovial sarcoma, translocated to x chromosome) (syt protein). [source:swissprot;acc:q15532]	2942	0.00001	0.00001	1	
star-related lipid transfer protein 13 (stard13) (start domain- containing protein 13) (46h23.2). [source:swissprot;acc:q9y3m8]	478	9649.61	11053.5	1.14549	
star-related lipid transfer protein 4 (stard4) (start domain- containing protein 4). [source:swissprot;acc:q96dr4]	1870	6076.66	6463.13	1.0636	
star-related lipid transfer protein 5 (stard5) (start domain- containing protein 5). [source:swissprot;acc:q9nsy2]	1865	6076.66	6463.12	1.0636	
star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [source:swissprot;acc:p59095]	1862	6076.66	6463.13	1.0636	
star-related lipid transfer protein 8 (stard8) (start domain- containing protein 8). [source:swissprot;acc:q92502]	479	9649.61	11053.5	1.14549	
ste20-like kinase; ste2-like kinase. [source:refseq;acc:nm_016281]	2980	0.00001	0.00001	1	
stem cell growth factor; lymphocyte secreted c-type lectin; lymphocyte secreted c-type lectin. [source:refseq;acc:nm_002975]	486	10908.6	12491.8	1.14513	
step ii splicing factor slu7. [source:refseq;acc:nm_006425]	661	5575.18	6254.85	1.12191	
sterile alpha and tir motif containing 1; sterile alpha and heat/armadillo motif protein, ortholog of drosophila. [source:refseq;acc:nm_015077]	1621	5520.36	5911.98	1.07094	
steroid hormone receptor err1 (estrogen-related receptor, alpha) (err-alpha) (estrogen receptor-like 1). [source:swissprot;acc:p11474]	905	10230.1	11256.2	1.1003	
steroid hormone receptor err2 (estrogen-related receptor, beta) (err-beta) (estrogen receptor-like 2) (err beta-2). [source:swissprot;acc:o95718]	875	10263.8	11318.6	1.10277	
steroidogenic factor 1 (stf-1) (sf-1) (steroid hormone receptor ad4bp) (fushi tarazu factor homolog 1). [source:swissprot;acc:q13285]	2972	0.00001	0.00001	1	
sterol regulatory element binding protein cleavage-activating protein (srebp cleavage-activating protein) (scap). [source:swissprot;acc:q12770]	868	5595.65	6173.23	1.10322	
sterol regulatory element binding protein-1 (srebp-1) (sterol regulatory element-binding transcription factor 1). [source:swissprot;acc:p36956]	712	5317.78	5944.25	1.11781	
sterol regulatory element binding protein-2 (srebp-2) (sterol regulatory element-binding transcription factor 2). [source:swissprot;acc:q12772]	711	5317.78	5944.25	1.11781	
stip1 homology and u-box containing protein 1; serologically defined colon cancer antigen 7; carboxy terminus of hsp70p-interacting protein; heat shock protein a binding protein 2 (c-terminal). [source:refseq;acc:nm_005861]	2350	6480.27	6765.81	1.04406	
stromal cell-derived factor 2 precursor (sdf-2). [source:swissprot;acc:q99470]	1804	4980.54	5307.81	1.06571	
stromal cell-derived factor 2-like protein 1 precursor (sdf2 like protein 1) (pwp1-interacting protein 8). [source:swissprot;acc:q9hcn8]	1805	4980.54	5307.81	1.06571	
stromal interaction molecule 1 precursor. [source:swissprot;acc:q13586]	2607	6380.61	6476.19	1.01498	
stromal interaction molecule 2 precursor. [source:swissprot;acc:q9p246]	2614	6380.61	6476.19	1.01498	
structure-specific recognition protein 1 (ssrp1) (recombination signal sequence recognition protein) (t160) (chromatin-specific transcription elongation factor 80 kda subunit) (fact 80 kda subunit). [source:swissprot;acc:q08945]	957	4483.26	4917.77	1.09692	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/