MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Value Type	Rank	Interaction Map	green	Network Comparison Type	network_comparison	Filtered	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Value Type	Rank	Interaction Map	green	network_comparison	Filtered	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Measured	37	High confidence	934.348	2.79409	0	334.401
		60		2765.82	1.6231	1	4489.19
		131	Low confidence	851.77	1.31954	0	645.504
		4914		7900.54	1.00597	1	7853.62
	Ranked	18	High confidence	245.247	1.32082		185.678
		242		13895.8	1.09822	0	15260.6
		629	Low confidence	13590.3	1.02915		13205.3
		4130		201.5	1.01062	1	199.383
	Squared	37	High confidence	1034.13	10.2338	0	101.05
		146	Low confidence	1268.51	1.63527		775.72
		245	High confidence	6768.05	1.31131	1	8875.01
		1119	Low confidence	41688.5	1.04654		43628.5
	Rooted	53	High confidence	18.0183	1.5213	0	11.844
		64		47.2654	1.35128	1	63.8686
		537	Low confidence	17.0804	1.04801	0	16.298
		4914		72.6287	1.00944	1	71.9496
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	Measured	509	High confidence	8630.06	1.14278		7551.8
		885	Low confidence	8585.64	1.03993		8255.95
	Ranked	1038	High confidence	181.041	1.03148		186.741
		1328	Low confidence	194.038	1.02218		198.342
	Squared	295	High confidence	39351.7	1.27733		30807.7
		4562	Low confidence	45736	1.01928		46617.7
	Rooted	805	High confidence	79.1513	1.0645		74.3557
		1092	Low confidence	76.3375	1.0386		73.5001
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	Measured	508	High confidence	8636.87	1.14293		7556.75
		880	Low confidence	8587.03	1.04001		8256.68
	Ranked	1032	High confidence	180.943	1.03162		186.664
		1322	Low confidence	194.014	1.0222		198.322
	Squared	294	High confidence	39383.9	1.2776		30826.5
		4569	Low confidence	45740.5	1.01914		46616.1
	Rooted	804	High confidence	79.1931	1.0646		74.3877
		1084	Low confidence	76.3467	1.03863		73.5068
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	Measured	237		9081.29	1.06457		8530.51
		514	High confidence	8532.02	1.1411		7477
	Ranked	588	Low confidence	185.859	1.03039		191.507
		1048	High confidence	182.308	1.031		187.96
	Squared	311		38866.5	1.27154		30566.4
		4138	Low confidence	47372.8	1.02676		46138.2
	Rooted	378		79.5804	1.04871		75.8843
		822	High confidence	78.5795	1.06393		73.8577
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	Measured	252	Low confidence	9018.94	1.06194		8492.92
		513	High confidence	8543.66	1.14143		7485.08
	Ranked	637	Low confidence	186.751	1.029		192.166
		1043	High confidence	182.137	1.03128		187.834
	Squared	308		38919.9	1.27205		30596.2
		4418	Low confidence	47088.3	1.02256		46049.4
	Rooted	427		79.1997	1.04731		75.6219
		811	High confidence	78.6514	1.06415		73.9102
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	Measured	2035	Low confidence	8323.04	1.03199		8065.05
	Ranked	3423		196.707	1.01523		199.702

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.