MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Network Comparison Type	Rank	red	Interaction Map	green	Value Type	network_comparison	Filtered

Results: HTML CSV LaTeX

Showing element 501 to 550 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Network Comparison Type	Rank	red	green	Value Type	network_comparison
40s ribosomal protein s13. [swissprot;acc:q02546]	Subtracted	936	21976	25607.9	Squared	3631.9
		1677	5414.98	5818.7	Measured	403.72
		1695	220.899	223.813	Ranked	2.914
		2361	60.5137	61.6019	Rooted	1.0882
40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366]	Divided	386	242.238	264.11	Ranked	1.09029
		530	50.6537	46.6413	Rooted	1.08603
		1823	13145.4	14424.1	Squared	1.09727
		2436	3708.67	3584.47	Measured	1.03465
	Subtracted	323	242.238	264.11	Ranked	21.872
		824	50.6537	46.6413	Rooted	4.0124
		2418	13145.4	14424.1	Squared	1278.7
		2520	3708.67	3584.47	Measured	124.2
40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	Divided	304	242.339	266.986	Ranked	1.1017
		376	50.2554	45.5688	Rooted	1.10285
		1989	12388.6	13523.5	Squared	1.09161
		2067	3602.75	3411.18	Measured	1.05616
	Subtracted	219	242.339	266.986	Ranked	24.647
		651	50.2554	45.5688	Rooted	4.6866
		2391	3602.75	3411.18	Measured	191.57
		2497	12388.6	13523.5	Squared	1134.9
40s ribosomal protein s15a. [swissprot;acc:p39027]	Divided	292	241.411	266.414	Ranked	1.10357
		366	50.5463	45.7763	Rooted	1.1042
		2008	3637.47	3435.61	Measured	1.05876
		2015	12467.2	13600.6	Squared	1.09091
	Subtracted	206	241.411	266.414	Ranked	25.003
		615	50.5463	45.7763	Rooted	4.77
		2368	3637.47	3435.61	Measured	201.86
		2502	12467.2	13600.6	Squared	1133.4
40s ribosomal protein s16. [swissprot;acc:p17008]	Divided	391	241.828	263.62	Ranked	1.09011
		534	50.8036	46.8198	Rooted	1.08509
		1784	13244.1	14564.4	Squared	1.09969
		2448	3730.53	3611.05	Measured	1.03309
	Subtracted	326	241.828	263.62	Ranked	21.792
		830	50.8036	46.8198	Rooted	3.9838
		2407	13244.1	14564.4	Squared	1320.3
		2528	3730.53	3611.05	Measured	119.48
40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	Divided	387	242.238	264.11	Ranked	1.09029
		531	50.6537	46.6413	Rooted	1.08603
		1824	13145.4	14424.1	Squared	1.09727
		2437	3708.67	3584.47	Measured	1.03465
	Subtracted	324	242.238	264.11	Ranked	21.872
		825	50.6537	46.6413	Rooted	4.0124
		2419	13145.4	14424.1	Squared	1278.7
		2521	3708.67	3584.47	Measured	124.2
40s ribosomal protein s19. [swissprot;acc:p39019]	Divided	771	55.6817	59.3786	Rooted	1.06639
		807	4708.61	5226.71	Measured	1.11003
		861	234.025	224.958	Ranked	1.04031
		1129	18854.4	21540.4	Squared	1.14246
	Subtracted	820	234.025	224.958	Ranked	9.067
		907	55.6817	59.3786	Rooted	3.6969

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.