MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Gene	Filtered	Rank	green	Value Type	Interaction Map	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 601 to 650 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	Rank	green	Value Type	Interaction Map	network_comparison	red
4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	1	1745	222.215	Ranked	High confidence	1.01272	219.423
		2352	61.9962	Rooted		1.01785	60.9091
		2696	193.541	Ranked	Low confidence	1.01757	196.941
		4943	48349.1	Squared		1.00446	48134.6
4-hydroxyphenylpyruvate dioxygenase (ec 1.13.11.27) (4hppd) (hpd) (hppdase). [swissprot;acc:p32754]		1057	74.502	Rooted		1.03873	71.724
		1132	8336.19	Measured		1.03689	8039.62
		1159	198.786	Ranked		1.02332	203.422
		4625	45456.1	Squared		1.01714	46235.3
40 kda peptidyl-prolyl cis-trans isomerase (ec 5.2.1.8) (ppiase) (rotamase) (cyclophilin-40) (cyp-40) (cyclophilin-related protein). [swissprot;acc:q08752]		1110	8628.8	Measured		1.03707	8320.39
		2376	76.2777	Rooted		1.03395	73.7734
		3251	194.871	Ranked		1.01583	197.955
		4792	46667.2	Squared		1.01124	47191.9
40s ribosomal protein s10. [swissprot;acc:p46783]	0	219	5302.97			1.27926	6783.9
		436	17.5674	Rooted		1.07201	18.8324
		488	13169.5	Ranked		1.06043	12419
		513	1135.73	Measured		1.05788	1201.47
	1	2273	44372	Squared		1.03879	46093.2
		3069	8233.31	Measured		1.0278	8010.65
		3077	74.0638	Rooted		1.03193	71.7722
		3263	199.593	Ranked		1.01576	202.739
40s ribosomal protein s11. [swissprot;acc:p04643]		278	267.088		High confidence	1.10642	241.399
		335	45.5342	Rooted		1.10841	50.4705
		1873	3402.09	Measured		1.0636	3618.46
		1939	39527.9	Squared	Low confidence	1.04067	41135.5
		2016	13514		High confidence	1.09081	12389
		3606	210.891	Ranked	Low confidence	1.01432	207.913
		4707	7472.14	Measured		1.01391	7369.62
		4898	69.4847	Rooted		1.01088	68.7371
40s ribosomal protein s12. [swissprot;acc:p25398]	0	560	11494.2	Ranked		1.04588	12021.5
		567	24.3289	Rooted		1.04129	23.3643
		661	2194.28	Measured		1.025	2140.77
		730	20717.3	Squared		1.02281	21189.8
	1	3133	42497.6			1.03476	43974.9
		3276	7995.94	Measured		1.027	7785.76
		3859	72.9222	Rooted		1.02828	70.9166
		4261	201.631	Ranked		1.0095	203.546
40s ribosomal protein s13. [swissprot;acc:q02546]		776	25607.9	Squared	High confidence	1.16527	21976
		1498	5818.7	Measured		1.07456	5414.98
		1722	223.813	Ranked		1.01319	220.899
		2348	61.6019	Rooted		1.01798	60.5137
		2851	8262.44	Measured	Low confidence	1.02878	8031.31
		3405	74.2382	Rooted		1.03059	72.0347
		3619	44427.7	Squared		1.03166	45834.3
		3777	199.227	Ranked		1.01335	201.886
40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366]		386	264.11		High confidence	1.09029	242.238
		530	46.6413	Rooted		1.08603	50.6537
		1823	14424.1	Squared		1.09727	13145.4
		2030	40034.4		Low confidence	1.04012	41640.7
		2436	3584.47	Measured	High confidence	1.03465	3708.67
		4334	7571.79		Low confidence	1.01967	7425.75

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.