MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Interaction Map	Filtered	Network Comparison Type	green	Value Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

Rank	description	Interaction Map	Filtered	green	Value Type	network_comparison	red
1	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	High confidence	0	15915	Ranked	3.70633	4294
	cab2. [refseq;acc:nm_033419]			7.16592	Squared	716592	0.00001
	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Low confidence	1	32	Ranked	2	16
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		0	1.87479	Squared	187479	0.00001
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]		1	23.3131	Rooted	2.10117	48.9847
				69.9153	Squared	19.4914	1362.75
				543.5	Measured	4.4149	2399.5
	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	High confidence	0	0.00001		36400000	364
					Rooted	1907880	19.0788
		Low confidence			Measured	36400000	364
					Rooted	1907880	19.0788
	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]			14977	Ranked	2.55362	5865
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	High confidence	1	24		2.4	10
	rad50-interacting protein 1. [refseq;acc:nm_021930]			48.9336	Rooted	2.30547	21.225
				1357.07	Squared	28.2513	48.0356
				2394.5	Measured	5.31521	450.5
2	cab2. [refseq;acc:nm_033419]		0	174		17400000	0.00001
	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Low confidence	1	23.3131	Rooted	2.10117	48.9847
				69.9153	Squared	19.4914	1362.75
				543.5	Measured	4.4149	2399.5
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		0	9.43398	Rooted	943398	0.00001
				89	Measured	8900000
	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]			1.87479	Squared	187479
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]		1	330	Ranked	1.47982	223
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	High confidence		28		1.86667	15
	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	Low confidence	0	21883		2.45711	8906
	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	High confidence		14977		2.55362	5865
	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]			0.00001	Squared	561325	5.61325
					Rooted	1240970	12.4097
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]		1	48.9336		2.30547	21.225
				1357.07	Squared	28.2513	48.0356
				2394.5	Measured	5.31521	450.5
3	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Low confidence		330	Ranked	1.47982	223
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]			23.3131	Rooted	2.10117	48.9847
				69.9153	Squared	19.4914	1362.75
				543.5	Measured	4.4149	2399.5
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	High confidence		28	Ranked	1.86667	15
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]			26.4292	Rooted	1.92839	50.9657
				115.48	Squared	13.8285	1596.92
				698.5	Measured	3.71868	2597.5
	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	Low confidence	0	1.87479	Squared	187479	0.00001
	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]			9.43398	Rooted	943398
				89	Measured	8900000
	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]			20617	Ranked	2.14604	9607
	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]	High confidence		11083.9		2.47638	4475.84
	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]			109	Measured	10900000	0.00001
	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]			0.00001	Squared	561325	5.61325
					Rooted	1240970	12.4097
4	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Low confidence	1	330	Ranked	1.47982	223
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	High confidence		28		1.86667	15

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.