MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Filtered	Rank	description	Value Type	Interaction Map	Network Comparison Type	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 2158 in total

Filtered  : 0
Network Comparison Type  : Subtracted
red  : 0

Rank	description	Value Type	Interaction Map	green	network_comparison
13	cab2. [refseq;acc:nm_033419]	Rooted	High confidence	13.1909	13.1909
17	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		Low confidence	9.43398	9.43398
18	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
19	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
25	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]		High confidence	10.4403	10.4403
26	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]		Low confidence	7.68115	7.68115
30	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		High confidence	9.43398	9.43398
31	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
32	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
52	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]			7.68115	7.68115
65	sedlin. [swissprot;acc:o14582]			6.55744	6.55744
66	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
116	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]			4.24264	4.24264
185	cab2. [refseq;acc:nm_033419]	Measured		174	174
265	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]			109	109
273	jumonji protein. [swissprot;acc:q92833]	Rooted	Low confidence	3.00407	3.00407
289	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	Measured	High confidence	89	89
290	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
291	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
342	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]			59	59
376	sedlin. [swissprot;acc:o14582]			43	43
377	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
402	cab2. [refseq;acc:nm_033419]	Squared		7.16592	7.16592
428	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Measured		18	18
429	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]	Squared		2.81207	2.81207
437	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]			1.87479	1.87479
438	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
439	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
450	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]			0.823905	0.823905
457	sedlin. [swissprot;acc:o14582]			0.437633	0.437633
458	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
461	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	Measured	Low confidence	89	89
462	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
463	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
470	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	Squared	High confidence	0.0766864	0.0766864
494	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured		0	0
		Squared
		Rooted
495	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured
		Squared
		Rooted
496	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured
		Squared
		Rooted
497	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured
		Squared
		Rooted
498	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.