Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Value Type Rank Network Comparison Type green red Filtered description Interaction Map network_comparison
Results: HTML CSV LaTeX Showing element 451 to 500 of 77072 in total
Value Type  : Measured
Rank
Network Comparison Type
green
red
Filtered
description
Interaction Map
network_comparison
57 Divided 2664.55 1631.67 1 kh domain containing, rna binding, signal transduction associated 3; sam68-like phosphotyrosine protein, t-star. [refseq;acc:nm_006558] High confidence 1.63302
17572.7 15464.1 homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483] Low confidence 1.13635
Subtracted 1729.7 2230.13 0 udp-glucuronosyltransferase 2b15 precursor, microsomal (ec 2.4.1.17) (udpgt) (udpgth-3) (hlug4). [swissprot;acc:p54855] High confidence 500.43
1973.79 2357.14 zinc finger protein 32 (zinc finger protein kox30) (fragment). [swissprot;acc:p17041] Low confidence 383.35
7600.25 6480.59 1 fos-related antigen 2. [swissprot;acc:p15408] 1119.66
24908.5 20911 ras-related gtp binding c; rag c protein. [refseq;acc:nm_022157] High confidence 3997.5
58 Divided 81.2233 150.741 0 40s ribosomal protein s26. [swissprot;acc:p02383] 1.85588
438.016 202.156 tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702] Low confidence 2.16672
2664.55 1631.67 1 kh domain containing, rna binding, signal transduction associated 1; gap-associated tyrosine phosphoprotein p62 (sam68). [refseq;acc:nm_006559] High confidence 1.63302
17572.7 15464.1 homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444] Low confidence 1.13635
Subtracted 1972.76 2356.02 0 zinc finger protein 95 homolog (zfp-95). [swissprot;acc:q9y2l8] 383.26
7600.61 6481.62 1 protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539] 1118.99
12011.7 11512.3 0 imp2 inner mitochondrial membrane protease-like; inner mitochondrial membrane peptidase 2 like. [refseq;acc:nm_032549] High confidence 499.4
24908.5 20911 1 ras-related gtp binding b short isoform; gtp-binding protein ragb. [refseq;acc:nm_006064] 3997.5
59 Divided 279.24 150.673 0 f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755] 1.85328
315.505 147.107 nadph oxidase, ef hand calcium-binding domain 5. [refseq;acc:nm_024505] Low confidence 2.14473
2664.55 1631.67 1 kh domain-containing, rna-binding, signal transduction-associated protein 2; sam68-like mammalian protein 1. [refseq;acc:nm_152688] High confidence 1.63302
17572.7 15464.1 homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630] Low confidence 1.13635
Subtracted 1972.55 2355.8 0 zinc finger protein 80 (znfpt17). [swissprot;acc:p51504] 383.25
7601.81 6485.05 1 fos-related antigen 1 (fra-1). [swissprot;acc:p15407] 1116.76
12011.7 11512.3 0 microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378] High confidence 499.4
24908.5 20911 1 anillin, actin binding protein (scraps homolog, drosophila); anillin (drosophila scraps homolog), actin binding protein. [refseq;acc:nm_018685] 3997.5
60 Divided 87.5499 47.4756 0 adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377] 1.8441
315.567 147.143 nadph oxidase homolog 1 (nox-1) (noh-1) (nadh/nadph mitogenic oxidase subunit p65-mox) (mitogenic oxidase 1) (mox1). [swissprot;acc:q9y5s8] Low confidence 2.14463
2765.82 4489.19 1 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] High confidence 1.6231
17572.7 15464.1 homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016] Low confidence 1.13635
Subtracted 1972.44 2355.67 0 zinc finger protein 187. [refseq;acc:nm_152736] 383.23
4827.7 5302.7 tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735] High confidence 475
12479.2 11371 1 tumor protein p53 inducible protein 3; quinone oxidoreductase homolog; p53-induced gene 3 protein. [refseq;acc:nm_004881] Low confidence 1108.2
12889.1 16771.5 ubiquitin activating enzyme e1-like protein. [refseq;acc:nm_006395] High confidence 3882.4
61 Divided 151 72 0 selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] Low confidence 2.09722
593.094 324.442 glutathione s-transferase theta 2 (ec 2.5.1.18) (gst class-theta). [swissprot;acc:p30712] High confidence 1.82804
2765.82 4489.19 1 glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216] 1.6231
17572.7 15464.1 homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067] Low confidence 1.13635
Subtracted 403.196 870.482 0 deltex homolog 1; hdx-1. [refseq;acc:nm_004416] High confidence 467.286
1972.44 2355.67 zinc finger protein 302 (znf135-like) (znf140-like). [swissprot;acc:q9nr11] Low confidence 383.23
7680.25 6614.51 1 transcription factor jun-d. [swissprot;acc:p17535] 1065.74
10307.5 6475.5 beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121] High confidence 3832
62 Divided 384.407 210.767 0 dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743] 1.82385
2765.82 4489.19 1 glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737] 1.6231
4356 2082 0 anchor attachment protein 1; glycophosphatidylinositol anchor attachment 1; anchor attachment protein 1 (gaa1p, yeast) homolog. [refseq;acc:nm_003801] Low confidence 2.09222
17572.7 15464.1 1 homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719] 1.13635
Subtracted 977 1442 0 putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7] High confidence 465
1972.28 2355.5 zinc finger protein zfp6 (fragment). [sptrembl;acc:q92967] Low confidence 383.22
7678.76 6613.42 1 transcription factor jun-b. [swissprot;acc:p17275] 1065.34
10307.5 6475.5 beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407] High confidence 3832
63 Divided 56.278 31.1429 0 spir-2 protein (fragment). [sptrembl;acc:q8wwl2] 1.80709
75.6508 154.208 laminin beta-1 chain precursor (laminin b1 chain). [swissprot;acc:p07942] Low confidence 2.03842
2765.82 4489.19 1 myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7] High confidence 1.6231
17572.7 15464.1 homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056] Low confidence 1.13635

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/