MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Gene	Filtered	Network Comparison Type	Rank	red	Interaction Map	green	network_comparison	description

Results: HTML CSV LaTeX

Showing element 1 to 50 of 19268 in total

Value Type  : Ranked
Filtered  : 0
Network Comparison Type  : Divided

Rank	red	Interaction Map	green	network_comparison	description
1	4294	High confidence	15915	3.70633	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]
	5865	Low confidence	14977	2.55362	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]
2		High confidence
	8906	Low confidence	21883	2.45711	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]
3	4475.84	High confidence	11083.9	2.47638	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]
	9607	Low confidence	20617	2.14604	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]
4	8906	High confidence	21883	2.45711	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]
	9607	Low confidence	20617	2.14604	neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]
5	5510.5	High confidence	11965.7	2.17144	ubiquitin-like protein smt3b (sentrin 2) (hsmt3). [swissprot;acc:p55855]
	10889.4	Low confidence	19873	1.82499	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
6	5575.71		9583.37	1.71877	trinucleotide repeat containing 15. [refseq;acc:nm_015575]
	7523	High confidence	15339.2	2.03897	ubiquitin protein ligase. [refseq;acc:nm_130466]
7	11543	Low confidence	6812	1.69451	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]
	21866	High confidence	10950	1.99689	cab2. [refseq;acc:nm_033419]
8	11525		21888	1.89918	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
	22286	Low confidence	13216	1.68629	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]
9	11525	High confidence	21888	1.89918	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]
	22286	Low confidence	13216	1.68629	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
10	7509.39	High confidence	14178.1	1.88805	fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757]
	22286	Low confidence	13216	1.68629	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
11	11627	High confidence	6248	1.86092	potential phospholipid-transporting atpase iia (ec 3.6.1.-). [swissprot;acc:o75110]
	13730.5	Low confidence	8257	1.66289	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
12	3190		1933	1.65028	anchor attachment protein 1; glycophosphatidylinositol anchor attachment 1; anchor attachment protein 1 (gaa1p, yeast) homolog. [refseq;acc:nm_003801]
	9429.18	High confidence	5208.84	1.81023	folylpolyglutamate synthase, mitochondrial precursor (ec 6.3.2.17) (folylpoly-gamma-glutamate synthetase) (fpgs). [swissprot;acc:q05932]
13	5210.5		9264.5	1.77804	heat shock 70 kda protein 1 (hsp70.1) (hsp70-1/hsp70-2). [swissprot;acc:p08107]
	7435.56	Low confidence	12191.6	1.63963	sorbitol dehydrogenase (ec 1.1.1.14) (l-iditol 2-dehydrogenase). [swissprot;acc:q00796]
14	10232.5	High confidence	18054.8	1.76446	dystrophin. [swissprot;acc:p11532]
	18050	Low confidence	11234	1.60673	ptd016 protein. [refseq;acc:nm_016125]
15	12074.1		7597.61	1.5892	adenomatous polyposis coli like. [refseq;acc:nm_005883]
	19403	High confidence	11267	1.72211	succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (cybs) (succinate-ubiquinone reductase membrane anchor subunit) (qps2) (cii-4) (succinate dehydrogenase complex subunit d) (succinate-ubiquinone oxidoreductase cytochrome b small subunit). [swissprot;acc:o14521]
16	7395	Low confidence	11625	1.57201	beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]
	12170.7	High confidence	20670.6	1.69839	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]
17	8082.33	Low confidence	5266.67	1.53462	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]
	11543	High confidence	6812	1.69451	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]
18	5850.23	Low confidence	8903.28	1.52187	early hematopoietic zinc finger. [refseq;acc:nm_015461]
	22286	High confidence	13216	1.68629	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]
19	3208.8	Low confidence	4871.6	1.5182	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]
	22286	High confidence	13216	1.68629	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
20					homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
	22422	Low confidence	14964	1.4984	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]
21	3859		2582	1.49458	dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]
	6313.38	High confidence	10621.4	1.68236	acrc protein; putative nuclear protein. [refseq;acc:nm_052957]
22	11515	Low confidence	7867	1.46371	cathepsin z precursor (ec 3.4.22.-) (cathepsin x) (cathepsin p). [swissprot;acc:q9ubr2]
	20989	High confidence	12479	1.68195	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]
23	14604.2	Low confidence	21138.6	1.44743	serpin b12. [swissprot;acc:q96p63]
	15520.4	High confidence	9285.44	1.67148	hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate. [refseq;acc:nm_004712]
24	13730.5		8257	1.66289	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
	14592	Low confidence	21113.7	1.44694	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]
25	9830		6909	1.42278	nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]
	13730.5	High confidence	8257	1.66289	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.