MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	description	Filtered	Gene	red	Rank	Value Type	Interaction Map	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

green  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted

description	Filtered	red	Rank	Value Type	network_comparison
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	1	0	3177	Rooted	0
ero1-like. [refseq;acc:nm_014584]	0	1.59148	440	Squared	1.59148
		9.05539	38	Rooted	9.05539
		82	316	Measured	82
erythroid differentiation-related factor 1. [refseq;acc:nm_015608]	1	0	3095		0
				Ranked
				Squared
				Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]			2868	Measured
				Ranked
				Squared
				Rooted
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]			2888	Measured
				Ranked
				Squared
				Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]			2781	Measured
				Ranked
				Squared
				Rooted
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]			3228	Measured
				Ranked
				Squared
				Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]			3181	Measured
				Ranked
				Squared
				Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]			3185	Measured
				Ranked
				Squared
				Rooted
fibrillin 1 precursor. [swissprot;acc:p35555]			2844	Measured
				Ranked
				Squared
				Rooted
fibrillin 2 precursor. [swissprot;acc:p35556]			2955	Measured
				Ranked
				Squared
				Rooted
fibrillin 3. [refseq;acc:nm_032447]			2939	Measured
				Ranked
				Squared
				Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]			2831	Measured
				Ranked
				Squared
				Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]			2907	Measured
				Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.