MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	description	Gene	Value Type	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Filtered  : 0
Network Comparison Type  : Divided

description	Value Type	Rank	network_comparison	Interaction Map	green	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Measured	37	2.79409	High confidence	934.348	334.401
		131	1.31954	Low confidence	851.77	645.504
	Ranked	242	1.09822	High confidence	13895.8	15260.6
		629	1.02915	Low confidence	13590.3	13205.3
	Squared	37	10.2338	High confidence	1034.13	101.05
		146	1.63527	Low confidence	1268.51	775.72
	Rooted	53	1.5213	High confidence	18.0183	11.844
		537	1.04801	Low confidence	17.0804	16.298
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	Measured	778	1.00902		4869.42	4825.89
	Ranked	627	1.02953		10050.9	10347.7
	Squared	815	1.00447		40451	40270.8
	Rooted	768	1.0106		39.5126	39.0982
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	Measured	19	11.6763	High confidence	26.1599	305.45
		171	1.22585	Low confidence	181.734	222.779
	Ranked	47	1.42943	High confidence	18499.2	12941.7
		384	1.08587	Low confidence	14695.2	13533.1
	Squared	26	128.828	High confidence	0.344399	44.3683
		697	1.03806	Low confidence	296.481	307.765
	Rooted	26	3.62106	High confidence	3.80565	13.7805
		131	1.20585	Low confidence	9.42485	11.365
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	Measured	451	1.01545	High confidence	2642.79	2683.61
		771	1.01017	Low confidence	1609.88	1593.68
	Ranked	379	1.03909	High confidence	10806	11228.4
		825	1.00181	Low confidence	11854.2	11832.8
	Squared	316	1.17196	High confidence	7355.46	8620.27
		763	1.01738	Low confidence	6490.54	6603.33
	Rooted	370	1.04188	High confidence	32.0298	30.7424
		793	1.00582	Low confidence	23.2445	23.11
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	Measured	474	1.00763	High confidence	2263.85	2281.12
		785	1.00797	Low confidence	2331.31	2349.9
	Ranked	495	1.00195	High confidence	11748.1	11725.2
		665	1.02285	Low confidence	11538	11801.6
	Squared	328	1.14785	High confidence	5878.56	6747.71
		591	1.07533	Low confidence	14694	15800.9
	Rooted	458	1.01531	High confidence	28.5146	28.0847
		728	1.01548	Low confidence	26.5693	26.1642
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Measured	492	1.00159	High confidence	5046.33	5038.33
		822		Low confidence
	Ranked	299	1.07178	High confidence	11512.3	12338.7
		453		Low confidence
	Squared	493	1	High confidence	17901.1	17901.1
		836		Low confidence
	Rooted	438	1.025	High confidence	44.9836	43.8864
		662		Low confidence
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	Measured	438	1.0252	High confidence	2853.65	2925.57
		581	1.04278	Low confidence	1932.95	2015.65
	Ranked	327	1.05751	High confidence	10466.5	9897.29
		501	1.0588	Low confidence	11352.1	10721.7
	Squared	477	1.0074	High confidence	18218.3	18353.1
		703	1.03494	Low confidence	10485.1	10851.4

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.