MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Value Type	Filtered	green	red	network_comparison	Interaction Map	Gene	Network Comparison Type	Rank

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

description	Value Type	Filtered	green	red	network_comparison	Interaction Map	Network Comparison Type	Rank
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	Ranked	1	197.22	200.982	1.01908	Low confidence	Divided	2163
					3.762		Subtracted	2149
			199.408	202.358	1.01479	High confidence	Divided	1637
					2.95		Subtracted	1682
	Squared		44326.9	46535.2	1.04982	Low confidence	Divided	864
					2208.3		Subtracted	797
			53788.1	59318.4	1.10282	High confidence	Divided	1721
					5530.3		Subtracted	453
	Rooted		74.792	72.3171	1.03422	Low confidence	Divided	2297
					2.4749		Subtracted	2260
			76.9113	74.9362	1.02636	High confidence	Divided	2059
					1.9751		Subtracted	1772
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	Measured		6349.04	5923.66	1.07181		Divided	1577
					425.38		Subtracted	1599
			8326.51	8088.12	1.02947	Low confidence	Divided	2711
					238.39		Subtracted	2526
	Ranked		197.374	200.312	1.01489		Divided	3515
					2.938		Subtracted	3521
			216.801	216.177	0.624	High confidence		2486
					1.00289		Divided	2478
	Squared		30113.9	27176.8	1.10807			1630
					2937.1		Subtracted	1280
			44345.7	45773.6	1.0322	Low confidence	Divided	3537
					1427.9		Subtracted	3429
	Rooted		64.5421	62.7515	1.02853	High confidence	Divided	1944
					1.7906		Subtracted	1968
			74.8438	72.5509	1.0316	Low confidence	Divided	3167
					2.2929		Subtracted	3092
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	Measured		6195.48	5826	1.06342	High confidence	Divided	1883
					369.48		Subtracted	1862
			8063.51	7825.14	1.03046	Low confidence	Divided	2447
					238.37		Subtracted	2527
	Ranked		199.229	204.36	1.02575		Divided	857
					5.131		Subtracted	830
			219.434	218.555	0.879	High confidence		2355
					1.00402		Divided	2368
	Squared		29969	26860.7	1.11572			1476
					3108.3		Subtracted	1182
			42544.1	44506	1.04611	Low confidence	Divided	1146
					1961.9		Subtracted	1379
	Rooted		63.5033	62.0038	1.02418	High confidence	Divided	2129
					1.4995		Subtracted	2140
			73.5808	70.8788	1.03812	Low confidence	Divided	1162
					2.702		Subtracted	1280
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	Measured	0	1609.88	1593.68	1.01017		Divided	771
					16.2		Subtracted	762
			2642.79	2683.61	1.01545	High confidence	Divided	451
					40.82		Subtracted	380
		1	6242.44	5826.74	1.07134		Divided	1609
					415.7		Subtracted	1646

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.