Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank description Network Comparison Type Value Type Interaction Map Filtered red network_comparison green
Results: HTML CSV LaTeX Showing element 451 to 500 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
red
network_comparison
green
226 cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] Divided 239.991 1.12187 269.238
protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378] Subtracted 242.153 24.52 266.673
227 methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582] 244.126 24.478 268.604
thrombospondin 3 precursor. [swissprot;acc:p49746] Divided 239.99 1.12186 269.234
228 methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579] Subtracted 244.126 24.478 268.604
sh2 domain containing 3c; novel sh2-containing protein 3; sh2 domain-containing 3c; likely ortholog of mouse cas/hef1-associated signal transducer. [refseq;acc:nm_005489] Divided 226.411 1.12036 202.088
229 60s ribosomal protein l3-like. [swissprot;acc:q92901] Subtracted 242.195 24.468 266.663
breast cancer antiestrogen resistance 3. [refseq;acc:nm_003567] Divided 226.401 1.12028 202.094
230 cysteine-rich protein 1 (crp1) (crp). [swissprot;acc:p21291] 239.35 1.11934 267.915
protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567] Subtracted 242.694 24.323 267.017
231 likely ortholog of mouse shc sh2-domain binding protein 1. [refseq;acc:nm_024745] Divided 239.336 1.11927 267.881
sh2 domain containing 3c; novel sh2-containing protein 3; sh2 domain-containing 3c; likely ortholog of mouse cas/hef1-associated signal transducer. [refseq;acc:nm_005489] Subtracted 226.411 24.323 202.088
232 breast cancer antiestrogen resistance 3. [refseq;acc:nm_003567] 226.401 24.307 202.094
smooth muscle cell lim protein (cysteine-rich protein 2) (crp2) (lim-only protein 5). [swissprot;acc:q16527] Divided 239.336 1.11926 267.879
233 60s ribosomal protein l7. [swissprot;acc:p18124] Subtracted 235.727 24.257 259.984
lim domain protein, cardiac (muscle lim protein) (cysteine-rich protein 3) (crp3). [swissprot;acc:p50461] Divided 239.32 1.11918 267.842
234 40s ribosomal protein s23. [swissprot;acc:p39028] Subtracted 243.944 24.251 268.195
chromatin accessibility complex protein 1 (chrac-1) (chrac-15) (huchrac15) (dna polymerase epsilon subunit p15). [swissprot;acc:q9nrg0] Divided 287.41 1.11905 256.835
235 28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235] Subtracted 243.944 24.251 268.195
phenylalanine-4-hydroxylase (ec 1.14.16.1) (pah) (phe-4- monooxygenase). [swissprot;acc:p00439] Divided 227.357 1.11785 254.15
236 histone acetyltransferase type b subunit 2 (retinoblastoma binding protein p46) (retinoblastoma-binding protein 7) (rbbp-7). [swissprot;acc:q16576] Subtracted 252.644 24.224 228.42
pp3111 protein. [refseq;acc:nm_022156] Divided 227.357 1.11785 254.15
237 mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001] Subtracted 242.011 24.169 266.18
syntaxin 18. [swissprot;acc:q9p2w9] Divided 227.357 1.11785 254.15
238 metastasis-associated protein mta1. [swissprot;acc:q13330] Subtracted 252.512 24.156 228.356
rd protein. [swissprot;acc:p18615] Divided 227.357 1.11785 254.15
239 dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [swissprot;acc:p24928] Subtracted 243.817 24.145 267.962
glutathione transferase omega 1 (ec 2.5.1.18) (gsto 1-1). [swissprot;acc:p78417] Divided 227.357 1.11785 254.15
240 androgen-induced 1; cgi-103 protein; androgen induced protein. [refseq;acc:nm_016108]
chromatin assembly factor 1 subunit c (caf-1 subunit c) (chromatin assembly factor i p48 subunit) (caf-i 48 kda subunit) (caf-ip48) (retinoblastoma binding protein p48) (retinoblastoma-binding protein 4) (rbbp-4) (msi1 protein homolog). [swissprot;acc:q09028] Subtracted 252.39 24.093 228.297
241 atp synthase b chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p24539] Divided 227.357 1.11785 254.15
epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830] Subtracted 241.892 24.068 265.96
242 c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02] 24.067 265.959
j domain containing protein 1. [swissprot;acc:q9ukb3] Divided 227.357 1.11785 254.15
243 60s ribosomal protein l23a. [swissprot;acc:p29316] Subtracted 241.884 24.061 265.945
sorting nexin 13 (rgs domain- and phox domain-containing protein) (rgs-px1). [swissprot;acc:q9y5w8] Divided 227.357 1.11785 254.15
244 60s ribosomal protein l5. [swissprot;acc:p46777] Subtracted 241.899 24.025 265.924
ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5] Divided 227.357 1.11785 254.15
245 60s ribosomal protein l19. [swissprot;acc:p14118] Subtracted 240.73 23.999 264.729
small nuclear ribonucleoprotein sm d3 (snrnp core protein d3) (sm-d3). [swissprot;acc:p43331] Divided 226.109 1.11751 202.333
246 60s ribosomal protein l12 like protein. [sptrembl;acc:o60886] Subtracted 243.583 23.945 267.528
eukaryotic translation initiation factor 4 gamma, 3. [refseq;acc:nm_003760] Divided 237.312 1.11748 212.363
247 60s ribosomal protein l12. [swissprot;acc:p30050] Subtracted 243.583 23.944 267.527
rna-binding protein. [refseq;acc:nm_019027] Divided 237.302 1.11719 212.41
248 apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576]
dj999l4.1 (novel protein similar to ribosomal protein l12 (rpl12)). [sptrembl;acc:q9nq02] Subtracted 243.583 23.944 267.527
249 ns1-associated protein 1. [refseq;acc:nm_006372] Divided 237.302 1.11719 212.41
small nuclear ribonucleoprotein sm d3 (snrnp core protein d3) (sm-d3). [swissprot;acc:p43331] Subtracted 226.109 23.776 202.333
250 heterogeneous nuclear ribonucleoprotein r (hnrnp r). [swissprot;acc:o43390] Divided 237.302 1.11719 212.41
pallidin; pallid (mouse) homolog, pallidin. [refseq;acc:nm_012388] Subtracted 210.693 23.743 186.95

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/